Evidence map›Paper›PMID 38550342›Full record

ArticleFrontiers in neurology2024

Exploring brain network oscillations during seizures in drug-naïve patients with juvenile absence epilepsy.

Linjie Tan, Haoling Tang, Hua Luo, Xiu Chen, Zhong Zheng, Jianghai Ruan, Dechou Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Linjie TanDepartment of Neurology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Haoling TangDepartment of Neurology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Hua LuoDepartment of Neurology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Xiu ChenDepartment of Neurology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Zhong ZhengNeurobiological Laboratory, West China Hospital, Sichuan University, Chengdu, China.
Jianghai RuanDepartment of Neurology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Dechou ZhangDepartment of Neurology, The Affiliated Traditional Chinese Medicine Hospital of Southwest Medical University, Luzhou, China.
Affiliated Hospital of Southwest Medical University · CNSichuan University · CNSouthwest Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: We aimed to investigate the brain network activity during seizures in patients with untreated juvenile absence epilepsy. Methods: Thirty-six juvenile absence epilepsy (JAE) patients with a current high frequency of seizures (more than five seizures during a 2 h EEG examination) were included. Each participant underwent a 2 h video EEG examination. Five 10 s EEG epochs for inter-ictal, pre-ictal, and post-ictal, and five 5 s EEG epochs for ictal states were extracted. Five 10 s resting-state EEG epochs for each participant from a sex- and age-matched healthy control (HC) were enrolled. The topological parameters of the brain networks were calculated using a graph theory analysis. Results: Compared with the resting state of the HC group, the global efficiency, local efficiency, and clustering coefficients of the JAE group decreased in the inter-ictal state. In addition, the ictal state showed significantly increased global and local efficiency and clustering coefficients ( Conclusion: The present study supported the idea that the changes in the EEG brain networks in JAE patients are characterized by decreased global and local efficiency and clustering coefficient in the alpha band. Moreover, the onset of seizures is accompanied by excessively enhanced network efficiency. JAE patients with different ictal discharge patterns may have different functional network oscillations.

Indexed as

electroencephalogramfunctional connectivitygraph theoryjuvenile absence epilepsyphase lock value

Identifiers

PMID38550342
PMCPMC10972980
OpenAlexW4392816620

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.