ArticleNPJ Parkinson's disease2024
Investigating the aspect of asymmetry in brain-first versus body-first Parkinson's disease.
Article in NPJ Parkinson's disease, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed.
- Equivocal Dopamine Transporter Imaging: Integrating Visual Assessment, Quantification, and Clinical Follow-Up.Life (Basel, Switzerland) · 2026Review
- Brain-first and body-first subtypes of Lewy body disease.Nature reviews. Neurology · 2026Review
- An exploratoryEuropean journal of nuclear medicine and molecular imaging · 2026Article
- A novel rat model of body first subtype of Parkinson's disease.bioRxiv : the preprint server for biology · 2026Article
- Exploring biomechanical differences between brain-first and body-first Parkinson's disease subtypes using shear wave elastography: a pilot cross-sectional study.Frontiers in aging neuroscience · 2026Article
- Striatal (a-)symmetry reveals sex-specific autonomic vulnerabilities in early Parkinson's disease.npj women's health · 2026Article
- Olfactory impairment and probable REM sleep behavior disorder in Parkinson's disease: clinical relevance to the single- and dual-hit hypotheses.Frontiers in aging neuroscience · 2026Article
- MRI structural and functional axial asymmetry in the brain-first versus body-first subtypes of Parkinson's disease.NPJ Parkinson's disease · 2025Article
- Discriminating between proposed Brain-First and Body-First Parkinson's disease using conventional and radiomics-enhanced dopamine transporter SPECT image analysis.NPJ Parkinson's disease · 2025Article
- IRMA: Machine learning-based harmonization ofEuropean journal of nuclear medicine and molecular imaging · 2025Article
- The Heart of the Matter: Cardiac Denervation Casts Doubt on the Brain-First Versus Body-First Hypothesis of Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- The Gut-Brain Axis Based on α-Synuclein Propagation-Clinical, Neuropathological, and Experimental Evidence.International journal of molecular sciences · 2025Review
- Is speech function lateralised in the basal ganglia? Evidence from de novo Parkinson's disease.Journal of neurology, neurosurgery, and psychiatry · 2025Article
- Quantitative 3D histochemistry reveals region-specific amyloid-β reduction by the antidiabetic drug netoglitazone.PloS one · 2025Article
- Rapid frontotemporal gray matter loss in proposed body-first Parkinson's disease: a longitudinal voxel-based morphometry study.Frontiers in neurology · 2025Article
- Exploring the relation between REM sleep behavior disorder onset and striatal dopaminergic dysfunction in Parkinson's Disease.Journal of neurology · 2024Article
- Comparison of vagus nerve cross-sectional area between brain-first and body-first Parkinson's disease.NPJ Parkinson's disease · 2024Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Parkinson's disease (PD) is characterized by a progressive loss of dopaminergic neurons in the substantia nigra. Recent literature has proposed two subgroups of PD. The "body-first subtype" is associated with a prodrome of isolated REM-sleep Behavior Disorder (iRBD) and a relatively symmetric brain degeneration. The "brain-first subtype" is suggested to have a more asymmetric degeneration and a prodromal stage without RBD. This study aims to investigate the proposed difference in symmetry of the degeneration pattern in the presumed body and brain-first PD subtypes. We analyzed
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.