Evidence map›Paper›PMID 38558655›Full record

ReviewCureus2024

Beneath the Surface: Exploring Hidden Threats of Long-Term Corticosteroid Therapy to Bone Density.

Sultan A Alfaedi, Majd F Kubbara, Abdullah A Alaithan, Hamad M Alhudhaif, Ahmed A Al Abdullah, Hussain M Sahool, Mohammed S Al Jawad, Mohammed A Almatar, Ibrahim R Alnakhli, Mohammed A Altawili

Open access · diamondAbstract readReview
In one paragraph

Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 3 countries.

Sultan A AlfaediOrthopedic Surgery, King Abdallah Medical Complex, Jeddah, SAU.
Majd F KubbaraGeneral Practice, Maternity and Children's Hospital, Dammam, SAU.
Abdullah A AlaithanGeneral Practice, Maternity and Children's Hospital, Dammam, SAU.
Hamad M AlhudhaifGeneral Practice, Ministry of Health, Riyadh, SAU.
Ahmed A Al AbdullahGeneral Practice, Omran General Hospital, Alahsa, SAU.
Hussain M SahoolOrthopaedics, King Faisal University, Qatif, SAU.
Mohammed S Al JawadGeneral Practice, Qatif Central Hospital, Qatif, SAU.
Mohammed A AlmatarOrthopedics Department, King Fahad Hospital, Jeddah, SAU.
Ibrahim R AlnakhliGeneral Practice, Maternity and Children Hospital, Medina , SAU.
Mohammed A AltawiliGeneral Practice, Alaziziyah Primary Health Care Center, Tabuk, SAU.
King Fahad Hospital Jeddah · SAQatif Central Hospital · SAHospital General de Almansa · ESKing Abdullah International Medical Research Center · SAKing Abdullah Medical City · SAMinistry of Health · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Within the field of medical treatments, corticosteroids are potent substances that efficiently reduce inflammation and immunological responses, making them essential for the management of a wide range of medical ailments. However, continued use of these synthetic drugs presents a serious risk: the onset of osteoporosis brought on by corticosteroids. Determining the complex pathways by which corticosteroids cause a general disturbance in bone metabolism, suppress osteoblast function, increase osteoclast activity, and upset the delicate balance of bone remodelling emphasizes the need for all-encompassing management and prevention approaches. In this review, we aim to expose the complexities of corticosteroid-induced bone loss and urge for personalized, proactive measures to improve long-term therapeutic outcomes.

Indexed as

bone densitybone lossbone mineral densitycorticosteroidcorticosteroid use

Identifiers

PMID38558655
PMCPMC10979079
OpenAlexW4392235162

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.