ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024
Fixel-Based Analysis Reveals Tau-Related White Matter Changes in Early Stages of Alzheimer's Disease.
Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed, 26 citations in OpenAlex.
- White matter microstructure and motor function in amnestic mild cognitive impairment and Alzheimer's dementia.Neuroimage. Reports · 2026Article
- Widespread white matter microstructural abnormalities in treatment‑naïve patients with first‑episode schizophrenia revealed by fixel-based analysis.Translational psychiatry · 2026Article
- Advanced diffusion MRI tract signatures in Alzheimer's disease, dementia with Lewy bodies, and the FTD/PPA spectrum.NeuroImage · 2026Review
- Amyloid-beta statuses prediction with free water MR imaging features in Alzheimer's disease using machine learning models.BMC medical imaging · 2026Article
- Accelerometer-measured physical activity, sedentary behavior, and incident neuropsychiatric diseases: a large prospective cohort study of 73411 participants.Molecular psychiatry · 2026Article
- Fixel‑based analysis reveals distributed white matter alterations associated with pain severity in trigeminal neuralgia.The journal of headache and pain · 2026Article
- Associations of modifiable and non-modifiable risk factors with longitudinal white matter hyperintensities, amyloid-β and tau - a prospective cohort study.The journal of prevention of Alzheimer's disease · 2026Observational
- Advanced neuroimaging assessment of neurodegenerative dementia syndromes: A framework for comprehensive multimodal FDG-PET, MR-perfusion, and MR-diffusion analysis.NeuroImage. Clinical · 2026Article
- White matter microstructure disruption associated with PET and cognitive impairment in Alzheimer's disease.PloS one · 2026Article
- White matter microstructural and macrostructural profiles during midlife reveal sex differences between men and women at different menopausal stages.Scientific reports · 2025Article
- Polygenic pathways shape white matter vulnerability to Alzheimer's disease-related pathophysiological changes.Alzheimer's research & therapy · 2025Article
- Utility of Harmonisation for Fixel-Based Metrics in Travelling Subjects and Alzheimer's Disease Data.Human brain mapping · 2025Article
- Impaired Glymphatic Clearance, Measured Using Diffusion Tensor Image Analysis Along the Perivascular Space (DTI-ALPS), is Linked to Poor Cognitive Outcomes in Parkinson's Disease.Movement disorders : official journal of the Movement Disorder Society · 2025Article
- White matter fractional anisotropy decreases precede hyperintensities in Alzheimer's disease.Cell reports. Medicine · 2025Article
- Fibre density and cross-section associate with hallmark pathology in early Alzheimer's disease.Alzheimer's research & therapy · 2025Article
- Artificial intelligence in neurodegenerative diseases research: a bibliometric analysis since 2000.Frontiers in neurology · 2025Review
- Microstructural mapping of neural pathways in Alzheimer's disease using macrostructure-informed normative tractometry.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025Article
- TDP-43-proteinopathy at the crossroads of tauopathy: on copathology and current and prospective biomarkers.Frontiers in cellular neuroscience · 2025Review
- Microstructural Mapping of Neural Pathways in Alzheimer's Disease using Macrostructure-Informed Normative Tractometry.bioRxiv : the preprint server for biology · 2024Article
- Neuroimaging and plasma evidence of early white matter loss in Parkinson's disease with poor outcomes.Brain communications · 2024Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Several studies have shown white matter (WM) abnormalities in Alzheimer's disease (AD) using diffusion tensor imaging (DTI). Nonetheless, robust characterization of WM changes has been challenging due to the methodological limitations of DTI. We applied fixel-based analyses (FBA) to examine microscopic differences in fiber density (FD) and macroscopic changes in fiber cross-section (FC) in early stages of AD (
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.