Evidence map›Paper›PMID 38566831›Full record

ArticleAlzheimer's & dementia (Amsterdam, Netherlands)

Normative data for the Digit Symbol Substitution for diverse Hispanic/Latino adults: Results from the Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA).

Alejandra Morlett Paredes, Wassim Tarraf, Kevin Gonzalez, Ariana M Stickel, Lisa V Graves, David P Salmon, Sonya S Kaur, Linda C Gallo, Carmen R Isasi, Richard B Lipton and 3 more

Open access · goldAbstract read
In one paragraph

Article in Alzheimer's & dementia (Amsterdam, Netherlands). The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Classifying cognitive status with TabCAT Match and UDS executive function tests.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Article
  3. Heterogeneity in cognitive profiles of monolingual and bilingual Hispanic/Latino older adults in HABS-HD.Journal of the International Neuropsychological Society : JINS · 2024
    Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Alejandra Morlett ParedesDepartment of Neurosciences UC San Diego La Jolla California USA.ORCID https://orcid.org/0000-0002-1027-537X
Wassim TarrafInstitute of Gerontology & Department of Healthcare Sciences Wayne State University Detroit Michigan USA.
Kevin GonzalezDepartment of Neurosciences UC San Diego La Jolla California USA.
Ariana M StickelDepartment of Psychology San Diego State University San Diego California USA.
Lisa V GravesDepartment of Psychology California State University San Marcos San Marcos California USA.
David P SalmonDepartment of Neurosciences UC San Diego La Jolla California USA.
Sonya S KaurDepartment of Neurology University of Miami Miami Florida USA.
Linda C GalloDepartment of Psychology San Diego State University San Diego California USA.
Carmen R IsasiDepartment of Epidemiology & Population Health Albert Einstein College of Medicine Bronx New York USA.
Richard B LiptonDepartment of Neurology Albert Einstein College of Medicine Bronx New York USA.
Melissa LamarRush Alzheimer's Disease Center Rush University Medical Center Chicago Illinois USA.
Zachary T GoodmanDepartment of Psychology University of Miami Miami Florida USA.
Hector M GonzálezDepartment of Neurosciences UC San Diego La Jolla California USA.
University of California San Diego · USAlbert Einstein College of Medicine · USSan Diego State University · USUniversity of Miami · USCalifornia State University, San Marcos · USRush University Medical Center · USWayne State University · US

Funding

Project 1U19AG024904 · NIA · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI MONICA G. RIVERA-MINDT · 2016 to 2026
$226.7M
UCSD Shiley-Marcos Alzheimer's Disease Research Center P30P30AG062429 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI JAMES B BREWER · 2019 to 2026
$34.9M
SDSU FUERTE: Recognition of Excellence in DEIA and Mentorship in support of Faculty SuccessU54CA267789 · NCI · SAN DIEGO STATE UNIVERSITY · PI Mark Brian Reed, Maria Luisa Zuniga de Nuncio · 2021 to 2026
$15.5M
Study of Latinos Investigation of Neurocognitive Aging 2R56AG048642 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI DECARLI, CHARLES, GONZALEZ, HECTOR M · 2020 to 2021
$8.7M
BEHAVIORAL MEDICINE RESEARCH IN CARDIOVASCULAR DISEASET32HL007426 · NHLBI · UNIVERSITY OF MIAMI CORAL GABLES · PI PENEDO, FRANK J · 1985 to 2023
$7.1M
UCSD Leading the Advancement of Underrepresented Neuroscientists for Change (LAUNCH) Faculty Development ProgramR25NS117367 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Victoria B Risbrough, Joann Trejo · 2020 to 2026
$1.6M
Risk Factors for Alzheimer's Disease Among Latinos: Relationships Between Cardiovascular Disease Risk, Acculturation, Small Vessel Disease, and Alzheimer's BiomarkersK08AG075351 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ariana Stickel · 2022 to 2026
$770k
NCI NIH HHS U54 CA267789NHGRI NIH HHS HHSN268201300003CNHLBI NIH HHS HHSN268201300001CNHLBI NIH HHS HHSN268201300003INHLBI NIH HHS HHSN268201300004CNHLBI NIH HHS HHSN268201300005CNHLBI NIH HHS T32 HL007426NIA NIH HHS K08 AG075351NIA NIH HHS L30 AG074401NIA NIH HHS P30 AG062429NIA NIH HHS R56 AG048642NIA NIH HHS U19 AG024904NINDS NIH HHS R25 NS117367
6 · The paper itself

Abstract

introductionExecutive functioning and processing speed are crucial elements of neuropsychological assessment. To meet the needs of the Hispanic/Latino population, we aimed to provide normative data for the Digit Symbol Substitution (DSS) test.

methodsThe target population for the Study of Latinos-Investigation of Neurocognitive Aging included six heritage backgrounds (

resultsAge, education, sex, heritage, and language preference were associated with DSS scores. DISCUSSION: Significant correlates of DSS performance should be considered when evaluating cognitive performance. Representative DSS norms for Hispanics/Latinos will advance assessment and accuracy of neurocognitive disorder diagnosis in clinical practice. To facilitate interpretation, we provide norms to reduce test biases and developed an online dashboard. Highlights: Normative data for the Digit Symbol Substitution (DSS) for diverse Hispanic/Latino adults: Results from the Study of Latinos-Investigation of Neurocognitive Aging (SOL-INCA) This study is the first to develop norms for the DSS test across four regions of the United States.Factors such as age, education, sex, and Hispanic/Latino heritage and language preference are associated with differences in executive functioning and information processing speed.We created norms and an online dashboard (https://solincalab.shinyapps.io/dsst_shiny/) providing an easily accessible tool to evaluate processing speed and executive functioning in Hispanic/Latino adults.

Indexed as

agingDigit Symbol Substitution testdisparitiesHispanicneuropsychologynormative data

Identifiers

PMID38566831
PMCPMC10983023
OpenAlexW4393387985

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.