ReviewFrontiers in pharmacology2024
Emerging insights into the impacts of heavy metals exposure on health, reproductive and productive performance of livestock.
Review in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 83 citations in OpenAlex.
- Circulating Elements in the Bloodstream of Growing Foals: Focus on Heavy Metals and Bone Remodeling Across Growth Stages.Biological trace element research · 2026Article
- Harnessing biostimulants to alleviate potentially toxic element stress in vegetable crops.Planta · 2026Review
- Dynamics of Toxic and Essential Element Transfer in Soil-Plant-Animal Systems Under Industrial Contamination.Biology · 2026Article
- Review on lead poisoning in domestic animals:Veterinary and animal science · 2026Review
- Heavy Metal-Driven Oral Dysbiosis: Salivary Toxicometallomics at the Host-Microbiome Interface Across Pathologies.Life (Basel, Switzerland) · 2026Review
- Effects of Pumpkin Seed Cake in Rabbit Diets on Blood Indices, Oxidative Status, and Trace Element Distribution in Tissues.Animals : an open access journal from MDPI · 2026Article
- Technogenic contamination of livestock- and fish-derived food products with heavy metals and radionuclides in industrial and post-nuclear regions of Kazakhstan.Veterinary world · 2026Article
- Environmental and Health Risk Assessments of Antibiotics and Heavy Metals in Manure in Liuyang City.Toxics · 2026Article
- A Heavy Metal and Trace Element Biomonitoring Study in a Young Cohort (Aged 18-24) in Istanbul, Turkey.International journal of environmental research and public health · 2026Article
- Anaemia, anthropometric status and associated factors among electronic waste recyclers, women and children residents of Agbogbloshie, Ghana.Discover public health · 2026Article
- Evaluation of arsenic, cobalt, nickel, lead, mercury, and titanium in goat blood and hair reared in Sicily and insights into blood biomarkers.Frontiers in veterinary science · 2026Article
- Cancer and Environmental Xenobiotics: Mechanisms, Controversies, and Innovations.Journal of xenobiotics · 2025Review
- Tracking copper-zinc and manganese superoxide dismutase in Avicennia marina reveals time-dependent expression of SOD isoforms in response to salt and lead stress.Scientific reports · 2025Article
- Hydrometallurgical extraction of zinc from wastes: optimization, feasibility and practical sustainable approach.Scientific reports · 2025Article
- Food chain risk assessment of cadmium accumulation and the relationships among diversely irrigated pasture-reared ruminants.Scientific reports · 2025Article
- Egg yolk-derived phosvitin as a natural chelator:Veterinary world · 2025Article
- Aflatoxin Exposure in Immunocompromised Patients: Current State and Future Perspectives.Toxins · 2025Review
- Impacts of Metals on Infectious Diseases in Wildlife and Zoonotic Spillover.Journal of xenobiotics · 2025Review
- Transplacental and genotoxicity effects of thallium(I) during organogenesis in mice.Toxicology reports · 2025Article
- Impact of Lead Pollution from Vehicular Traffic on Highway-Side Grazing Areas: Challenges and Mitigation Policies.International journal of environmental research and public health · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Heavy metals, common environmental pollutants with widespread distribution hazards and several health problems linked to them are distinguished from other toxic compounds by their bioaccumulation in living organisms. They pollute the food chain and threaten the health of animals. Biologically, heavy metals exhibit both beneficial and harmful effects. Certain essential heavy metals such as Co, Mn, Se, Zn, and Mg play crucial roles in vital physiological processes in trace amounts, while others like As, Pb, Hg, Cd, and Cu are widely recognized for their toxic properties. Regardless of their physiological functions, an excess intake of all heavy metals beyond the tolerance limit can lead to toxicity. Animals face exposure to heavy metals through contaminated feed and water, primarily as a result of anthropogenic environmental pollution. After ingestion heavy metals persist in the body for an extended duration and the nature of exposure dictates whether they induce acute or chronic, clinical or subclinical, or subtle toxicities. The toxic effects of metals lead to disruption of cellular homeostasis through the generation of free radicals that develop oxidative stress. In cases of acute heavy metal poisoning, characteristic clinical symptoms may arise, potentially culminating in the death of animals with corresponding necropsy findings. Chronic toxicities manifest as a decline in overall body condition scoring and a decrease in the production potential of animals. Elevated heavy metal levels in consumable animal products raise public health concerns. Timely diagnosis, targeted antidotes, and management strategies can significantly mitigate heavy metal impact on livestock health, productivity, and reproductive performance.
Indexed as
Identifiers
What Socratic holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.