Evidence map›Paper›PMID 38568418›Full record

ArticleMolecular neurobiology2024

Synthesis of Novel Plant-Derived Encapsulated Radiolabeled Compounds for the Diagnosis of Parkinson's Disease and the Evaluation of Biological Effects with In Vitro/In Vivo Methods.

Emre Uygur, Kadriye Büşra Karatay, Emine Derviş, Vedat Evren, Ayfer Yurt Kılçar, Özge Kozguş Güldü, Ceren Sezgin, Burcu Acar Çinleti, Volkan Tekin, Fazilet Zumrut Biber Muftuler

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular neurobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Emre Uygur *Soma Vocational School, Department of Biomedical Device Technologies, Manisa Celal Bayar University, Nihat Danışman, Değirmen Cd. No. 2, Soma, 45500, Manisa, Turkey. emre.uygur@cbu.edu.tr.ORCID http://orcid.org/0000-0002-8695-8759
Kadriye Büşra Karatay *Institute of Nuclear Sciences, Ege University, Erzene, Ege Üniversitesi, Ege Ünv., 35100, Bornova, İzmir, Turkey.
Emine Derviş *Institute of Nuclear Sciences, Ege University, Erzene, Ege Üniversitesi, Ege Ünv., 35100, Bornova, İzmir, Turkey.
Vedat Evren *Faculty of Medicine, Department of Physiology, Ege University, Bornova, 35100, İzmir, Turkey.
Ayfer Yurt Kılçar *Institute of Nuclear Sciences, Ege University, Erzene, Ege Üniversitesi, Ege Ünv., 35100, Bornova, İzmir, Turkey.
Özge Kozguş Güldü *Institute of Nuclear Sciences, Ege University, Erzene, Ege Üniversitesi, Ege Ünv., 35100, Bornova, İzmir, Turkey.
Ceren SezginDepartment of Nuclear Medicine, Manisa City Hospital, Adnan Menderes Neighborhood, 132Nd Street Number 15 Şehzadeler, 45100, Manisa, Turkey.
Burcu Acar ÇinletiFaculty of Medicine, Buca Seyfi Demirsoy Training and Research Hospital, Department of Neurology, Izmir Democracy University, Kozağaç Mah. Özmen Cad. No. 147, Buca, 35040, Izmir, Turkey.
Volkan Tekin *Institute of Nuclear Sciences, Ege University, Erzene, Ege Üniversitesi, Ege Ünv., 35100, Bornova, İzmir, Turkey.
Fazilet Zumrut Biber Muftuler *Institute of Nuclear Sciences, Ege University, Erzene, Ege Üniversitesi, Ege Ünv., 35100, Bornova, İzmir, Turkey.
Ege University · TRIzmir University · TRManisa Celal Bayar University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parkinson's disease (PD) is a neurodegenerative disorder that affects millions of individuals globally. It is characterized by the loss of dopaminergic neurons in Substantia Nigra pars compacta (SNc) and striatum. Neuroimaging techniques such as single-photon emission computed tomography (SPECT), positron emission tomography (PET), and magnetic resonance imaging (MRI) help diagnosing PD. In this study, the focus was on developing technetium-99 m ([

Indexed as

Parkinson DiseaseAnimalsCell Line, TumorHumansLevodopaMalePC12 CellsPolylactic Acid-Polyglycolic Acid CopolymerRatsRats, Sprague-DawleyTechnetiumTissue DistributionLevodopaPolylactic Acid-Polyglycolic Acid CopolymerTechnetium[99mTc]TcEncapsulationIn vitroIn vivoL-DOPAMadecassoside (MA)Parkinson’s diseasePLGA

Identifiers

PMID38568418
PMCPMC11496352
OpenAlexW4393860963

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.