Evidence map›Paper›PMID 38568450›Full record

ArticleCellular and molecular neurobiology2024

Mitochondrial Calcium Uniporter (MCU) is Involved in an Ischemic Postconditioning Effect Against Ischemic Reperfusion Brain Injury in Mice.

Hiromitsu Sasaki, Ichiro Nakagawa, Takanori Furuta, Shohei Yokoyama, Yudai Morisaki, Yasuhiko Saito, Hiroyuki Nakase

Open access · hybridAbstract read
In one paragraph

Article in Cellular and molecular neurobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.4field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Role of mitochondrial CaMolecular medicine reports · 2025
    Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Hiromitsu SasakiDepartment of Neurosurgery, Nara Medical University, Shijo-Cho 840, Kashihara City, Nara, 634-8522, Japan.ORCID http://orcid.org/0009-0002-6943-4811
Ichiro NakagawaDepartment of Neurosurgery, Nara Medical University, Shijo-Cho 840, Kashihara City, Nara, 634-8522, Japan. nakagawa@naramed-u.ac.jp.ORCID http://orcid.org/0000-0002-1340-3293
Takanori FurutaDepartment of Neurosurgery, Nara Medical University, Shijo-Cho 840, Kashihara City, Nara, 634-8522, Japan.ORCID http://orcid.org/0000-0002-9839-2262
Shohei YokoyamaDepartment of Neurosurgery, Nara Medical University, Shijo-Cho 840, Kashihara City, Nara, 634-8522, Japan.ORCID http://orcid.org/0000-0002-1849-4200
Yudai MorisakiDepartment of Neurosurgery, Nara Medical University, Shijo-Cho 840, Kashihara City, Nara, 634-8522, Japan.ORCID http://orcid.org/0000-0002-6348-2372
Yasuhiko SaitoDepartment of Neurophysiology, Nara Medical University, Shijo-Cho 840, Kashihara City, Nara, 634-8522, Japan.ORCID http://orcid.org/0000-0002-0148-6597
Hiroyuki NakaseDepartment of Neurosurgery, Nara Medical University, Shijo-Cho 840, Kashihara City, Nara, 634-8522, Japan.ORCID http://orcid.org/0000-0002-2726-5960
Nara Medical University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The phenomenon of ischemic postconditioning (PostC) is known to be neuroprotective against ischemic reperfusion (I/R) injury. One of the key processes in PostC is the opening of the mitochondrial ATP-dependent potassium (mito-K

Indexed as

Brain InjuriesCalcium ChannelsIschemic PostconditioningRuthenium CompoundsAdenosine TriphosphateAnimalsMiceMice, Inbred C57BLReceptors, N-Methyl-D-AspartateAdenosine TriphosphateCalcium Channelsmitochondrial calcium uniporterReceptors, N-Methyl-D-AspartateRu265Ruthenium CompoundsIschemic postconditioning (PostC)Mitochondrial calcium uniporter (MCU)Mitochondrial permeability transition pore (mPTP)NMDA receptor (NMDAR)

Identifiers

PMID38568450
PMCPMC10991049
OpenAlexW4393861101

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.