ArticleScience advances2024
Drp1 controls complex II assembly and skeletal muscle metabolism by Sdhaf2 action on mitochondria.
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In one paragraph
Article in Science advances, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
18 citing papers in PubMed, 14 citations in OpenAlex.
- FOXP1 exacerbates allergic rhinitis progression by mediating ferroptosis in nasal mucosal epithelial cells via transcriptional regulation of SDHAF2.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026Article
- Systems modelling of mitochondrial dynamics in different exercise regimes.The Journal of physiology · 2026Article
- Review
- Drp1 regulates mitochondrial health and controls skeletal muscle mass through the Erk1/2-Nur77 pathway.Science advances · 2026Article
- Reactive oxygen species (ROS) in cancer: from mechanism to therapeutic implications.Signal transduction and targeted therapy · 2026Review
- Morphological and structural alterations in skeletal muscle of STZ-induced diabetic rats revealed by light and electron microscopy.Journal of advanced veterinary and animal research · 2026Article
- The "Mechano-Metabolic-Immune" crosstalk within the skeletal muscle microenvironment: evolution of homeostatic remodeling and quality control mechanisms.Frontiers in immunology · 2026Review
- Review
- Roles of DRP1 and the fission protein interactome as regulators of cellular stability and sarcopenia in skeletal muscle aging.Aging advances · 2025Article
- ROS-Drp1-mitophagy feedback loop regulates myogenic differentiation via actin cytoskeleton remodeling-mediated MRTF-A/SRF axis.Redox report : communications in free radical research · 2025Article
- HSV-1 hijacks mitochondrial dynamics: potential molecular mechanisms linking viral infection to neurodegenerative disorders.Apoptosis : an international journal on programmed cell death · 2025Review
- Ankyrin-B modulates mitochondrial fission in skeletal muscle and is required for optimal endurance exercise capacity.Nature communications · 2025Article
- Fructose-Induced Impairment of Liver and Skeletal Muscle Metabolism Is Prevented by Administration of Shouchella clausii Spores by Preserving Mitochondrial Function and Insulin Sensitivity.Molecular nutrition & food research · 2025Article
- Muscle metabolic resilience and enhanced exercise adaptation by Esr1-induced remodeling of mitochondrial cristae-nucleoid architecture in males.Cell reports. Medicine · 2025Article
- SIRT5 safeguards against primate skeletal muscle ageing via desuccinylation of TBK1.Nature metabolism · 2025Article
- The Role of Mitochondrial Quality Control in Liver Diseases: Dawn of a Therapeutic Era.International journal of biological sciences · 2025Review
- Prognostic value and immunomodulatory role of DNM1L in gastric adenocarcinoma.Frontiers in oncology · 2024Article
- Exploring and Validating the Molecular Mechanisms Linking Fatty Acid Metabolism and Sarcopenia.IET systems biologyArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 4 institutions in 2 countries.
Zhenqi ZhouDivision of Endocrinology, Diabetes and Hypertension, Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0001-6560-9704
Alice MaDivision of Endocrinology, Diabetes and Hypertension, Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0009-0002-8777-8044
Timothy M MooreDivision of Endocrinology, Diabetes and Hypertension, Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0003-4250-3370
Dane M WolfDivision of Endocrinology, Diabetes and Hypertension, Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Nicole YangDivision of Endocrinology, Diabetes and Hypertension, Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0002-6684-7939
Peter TranDivision of Endocrinology, Diabetes and Hypertension, Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0003-4467-2055
Mayuko SegawaDivision of Endocrinology, Diabetes and Hypertension, Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0002-5680-9576
Alexander R StrumwasserDivision of Endocrinology, Diabetes and Hypertension, Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Wenjuan RenDivision of Endocrinology, Diabetes and Hypertension, Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Kai FuDepartment of Molecular, Cell and Developmental Biology, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0002-8107-3556
Jonathan WanagatDivision of Geriatrics, Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0002-8460-8616
Alexander M van der BliekDepartment of Biological Chemistry, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0002-6211-5765
Rachelle H CrosbieDepartment of Integrative Biology and Physiology, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Marc LiesaDivision of Endocrinology, Diabetes and Hypertension, Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0002-5909-8570
Linsey StilesDivision of Endocrinology, Diabetes and Hypertension, Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Rebecca Acin-PerezDivision of Endocrinology, Diabetes and Hypertension, Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0001-9553-8337
Sushil MahataVA San Diego Healthcare System, San Diego, CA 92161, USA.ORCID 0000-0002-9154-0787
Orian ShirihaiDivision of Endocrinology, Diabetes and Hypertension, Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0001-8466-3431
Mark O GoodarziDivision of Endocrinology, Diabetes and Metabolism, Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90095, USA.ORCID 0000-0001-6364-5103
Michal HandzlikInstitute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.
Christian M MetalloInstitute of Engineering in Medicine, University of California, San Diego, La Jolla, CA 92093, USA.ORCID 0000-0003-2404-3040
David W WalkerMolecular Biology Institute, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Andrea L HevenerDivision of Endocrinology, Diabetes and Hypertension, Department of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0003-1508-4377
University of California, Los Angeles · USUniversity of California San Diego · USCedars-Sinai Medical Center · USSalk Institute for Biological Studies · US
Funding
Transgenic & Knock-out MouseP30DK063491 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ALAN R. SALTIEL · 2003 to 2026
$40.4MRole of Mitochondrial Homeostasis in Animal AgingR01AG037514 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI David W Walker · 2010 to 2026
$5.3MRole of dynamin-related protein 1 in the regulation of metabolism and skeletal muscle massR01DK125354 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI ZHOU, ZHENQI · 2021 to 2025
$2.5MRole of Intestinal Homeostasis in Organismal Aging.R01AG049157 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WALKER, DAVID W · 2015 to 2025
$2.4MMechanisms controlling skeletal muscle mitochondrial function and metabolic healthR01DK109724 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HEVENER, ANDREA L · 2016 to 2020
$2.4MRole of Intestinal Homeostasis in Organismal AgingRF1AG049157 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI WALKER, DAVID W · 2021 to 2021
$1.2MJEOL JEM-1400Plus Transmission Electron MicroscopeS10OD023527 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI FARQUHAR, MARILYN GIST · 2017 to 2017
$579kNIA NIH HHS R01 AG037514NIA NIH HHS R01 AG049157NIA NIH HHS RF1 AG049157NIDDK NIH HHS P30 DK063491NIDDK NIH HHS R01 DK109724NIDDK NIH HHS R01 DK125354NIH HHS S10 OD023527
Abstract
The dynamin-related guanosine triphosphatase, Drp1 (encoded by
Indexed as
InsulinsSuccinate DehydrogenaseAnimalsDynaminsHumansLipidsMaleMiceMitochondriaMitochondrial ProteinsMuscle, SkeletalDnm1l protein, mouseDynaminsInsulinsLipidsMitochondrial ProteinsSuccinate Dehydrogenase
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY-NC
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.