Evidence map›Paper›PMID 38569908›Full record

ArticleInternal medicine (Tokyo, Japan)2024

A Cerebral Embolism Caused by a Malignant Peripheral Nerve Sheath Tumor in a Patient with Neurofibromatosis Type 1.

Kyosuke Matsunaga, Muneaki Kikuno, Hiroki Sakamoto, Hirofumi Okada, Takao Hashimoto, Shogo Honda, Jun Matsubayashi, Toshitaka Nagao, Yuko Yamada, Hajime Horiuchi and 4 more

Open access · diamondAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Kyosuke MatsunagaDepartment of Neurosurgery, Tokyo Medical University Hospital, Japan.
Muneaki KikunoDepartment of Neurosurgery, Tokyo Medical University Hospital, Japan.
Hiroki SakamotoDepartment of Neurosurgery, Tokyo Medical University Hospital, Japan.
Hirofumi OkadaDepartment of Neurosurgery, Tokyo Medical University Hospital, Japan.
Takao HashimotoDepartment of Neurosurgery, Tokyo Medical University Hospital, Japan.
Shogo HondaDepartment of Anatomic Pathology, Tokyo Medical University, Japan.
Jun MatsubayashiDepartment of Anatomic Pathology, Tokyo Medical University, Japan.
Toshitaka NagaoDepartment of Anatomic Pathology, Tokyo Medical University, Japan.
Yuko YamadaDepartment of Molecular Pathology, Tokyo Medical University, Japan.
Hajime HoriuchiDepartment of Molecular Pathology, Tokyo Medical University, Japan.
Masahiko KurodaDepartment of Molecular Pathology, Tokyo Medical University, Japan.
Shigeo MurayamaDepartment of Neuropathology (Brain Bank for Aging Research), Tokyo Metropolitan Institute for Geriatrics and Gerontology, Japan.
Hiroo TerashiDepartment of Neurology, Tokyo Medical University Hospital, Japan.
Michihiro KohnoDepartment of Neurosurgery, Tokyo Medical University Hospital, Japan.
Tokyo Medical University Hospital · JPTokyo Medical University · JPTokyo Metropolitan Institute of Gerontology · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 31-year-old man with neurofibromatosis type 1 (NF-1) had undergone resection of a malignant peripheral nerve sheath tumor (MPNST) on the buttock 3 months previously. He subsequently underwent mechanical thrombectomy for a hyperacute left middle cerebral artery embolism. Histopathologically, the emboli comprised neurofilament-positive pleomorphic tumor cells with geographic necrosis and conspicuous mitosis and were identified as MPNST. The patient died of respiratory failure due to lung MPNST metastasis on day 15 of hospitalization. To our knowledge, this is the first report of a spontaneous cerebral embolism due to MPNST in an NF-1 patient.

Indexed as

Intracranial EmbolismNerve Sheath NeoplasmsNeurofibromatosis 1AdultFatal OutcomeHumansMalecerebral embolismmalignant peripheral nerve sheath tumormechanical thrombectomyneurofibromatosis type 1

Identifiers

PMID38569908
PMCPMC11637803
OpenAlexW4393395298

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.