Evidence map›Paper›PMID 38570189›Full record

ArticleLife science alliance2024

Human CRB1 and CRB2 form homo- and heteromeric protein complexes in the retina.

Isabel F Stehle, Joel A Imventarza, Franziska Woerz, Felix Hoffmann, Karsten Boldt, Tina Beyer, Peter Mj Quinn, Marius Ueffing

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Metabolomic signatures suggest altered bile acid and energy metabolism in CRB1- retinopathies.Metabolomics : Official journal of the Metabolomic Society · 2026
    Article
  3. Variant-to-gene mapping identifiesbioRxiv : the preprint server for biology · 2026
    Article
  4. Novel Genotype-Phenotype Correlations inOphthalmology science · 2026
    Article
  5. Article
  6. Article
  7. Diverse functions and pathogenetic role of Crumbs in retinopathy.Cell communication and signaling : CCS · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Isabel F StehleInstitute for Ophthalmic Research, Eberhard Karls University Tübingen, Tübingen, Germany.ORCID 0009-0006-0957-5144
Joel A ImventarzaDepartment of Ophthalmology, Vagelos College of Physicians & Surgeons, Columbia University; New York, NY, USA.ORCID 0000-0003-2861-1658
Franziska WoerzInstitute for Ophthalmic Research, Eberhard Karls University Tübingen, Tübingen, Germany.ORCID 0009-0007-5484-358X
Felix HoffmannInstitute for Ophthalmic Research, Eberhard Karls University Tübingen, Tübingen, Germany.ORCID 0000-0001-5199-2749
Karsten BoldtInstitute for Ophthalmic Research, Eberhard Karls University Tübingen, Tübingen, Germany.ORCID 0000-0002-2693-689X
Tina BeyerInstitute for Ophthalmic Research, Eberhard Karls University Tübingen, Tübingen, Germany.ORCID 0000-0002-6302-8997
Peter Mj QuinnDepartment of Ophthalmology, Vagelos College of Physicians & Surgeons, Columbia University; New York, NY, USA.ORCID 0000-0001-9940-4264
Marius UeffingInstitute for Ophthalmic Research, Eberhard Karls University Tübingen, Tübingen, Germany marius.ueffing@uni-tuebingen.de.ORCID 0000-0003-2209-2113
University of Tübingen · DENew York Proton Center · US

Funding

Prime editing for Crumbs homologue 1 (CRB1) Inherited Retinal DystrophiesR01EY034952 · NEI · UNIVERSITY OF PENNSYLVANIA · PI Peter Martin John Quinn · 2023 to 2026
$1.6M
NEI NIH HHS R01 EY034952Wellcome Trust
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Leber Congenital AmaurosisRetinitis PigmentosaAnimalsCarrier ProteinsEye ProteinsHumansMembrane ProteinsNerve Tissue ProteinsRetinaZebrafishCarrier ProteinsCRB1 protein, humanCRB2 protein, humanEye ProteinsMembrane ProteinsNerve Tissue Proteins

Identifiers

PMID38570189
PMCPMC10992996
OpenAlexW4393862640

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.