Evidence map›Paper›PMID 38570518›Full record

ArticleTranslational psychiatry2024

Immunogenetics of lithium response and psychiatric phenotypes in patients with bipolar disorder.

Marisol Herrera-Rivero, Karina Gutiérrez-Fragoso, International Consortium on Lithium Genetics (ConLi+Gen), Joachim Kurtz, Bernhard T Baune

Open access · goldAbstract read
In one paragraph

Article in Translational psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Exploring the genetics of lithium response in bipolar disorders.International journal of bipolar disorders · 2024
    Article
  9. Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 20 institutions in 17 countries.

Marisol Herrera-RiveroDepartment of Psychiatry and Psychotherapy, University of Münster, Münster, Germany.ORCID 0000-0001-7064-9487
Karina Gutiérrez-FragosoDivision of Engineering in Computational Systems, Higher Technological Institute of the East of the State of Hidalgo, Hidalgo, Mexico.ORCID 0000-0002-4968-0188
International Consortium on Lithium Genetics (ConLi+Gen)
Joachim KurtzJoint Institute for Individualisation in a Changing Environment (JICE), University of Münster and Bielefeld University, Münster, Germany.ORCID 0000-0002-7258-459X
Bernhard T BauneDepartment of Psychiatry and Psychotherapy, University of Münster, Münster, Germany. Bernhard.Baune@ukmuenster.de.
Centro de Investigación Biomédica en Red de Salud Mental · ESMedical University of Graz · ATPoznan University of Medical Sciences · PLUniversity of Bonn · DEJohns Hopkins University · USUniversity of Cagliari · ITUNSW Sydney · AUCentre Hospitalier Charles Perrens · FRDokkyo Medical University · JPInserm · FRKarolinska Institutet · SENational Institutes of Health · USThe University of Adelaide · AUUniversity of Geneva · CHLudwig-Maximilians-Universität München · DEBielefeld University · DEDalhousie University · CAGoethe University Frankfurt · DEInstituto de Salud Carlos III · ESMayo Clinic · US

Funding

BLRD VA I01 BX003431DBT-Wellcome Trust India Alliance IA/CPHI/20/1/505266
6 · The paper itself

Abstract

The link between bipolar disorder (BP) and immune dysfunction remains controversial. While epidemiological studies have long suggested an association, recent research has found only limited evidence of such a relationship. To clarify this, we performed an exploratory study of the contributions of immune-relevant genetic factors to the response to lithium (Li) treatment and the clinical presentation of BP. First, we assessed the association of a large collection of immune-related genes (4925) with Li response, defined by the Retrospective Assessment of the Lithium Response Phenotype Scale (Alda scale), and clinical characteristics in patients with BP from the International Consortium on Lithium Genetics (ConLi

Indexed as

Bipolar DisorderGlycogen Synthase Kinase 3 betaHumansImmunogeneticsLithiumPhenotypeRetrospective StudiesGlycogen Synthase Kinase 3 betaLithium

Identifiers

PMID38570518
PMCPMC10991481
OpenAlexW4393862200

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.