Evidence map›Paper›PMID 38573125›Full record

Observational studyRadiology. Cardiothoracic imaging2024

Association of Coronary Wall Thickening and Diminished Diastolic Function in Asymptomatic, Low Cardiovascular Disease-Risk Persons Living with HIV.

Khaled Z Abd-Elmoniem, Hadjira Ishaq, Julia Purdy, Jatin Matta, Ahmed Hamimi, Hwaida Hannoush, Colleen Hadigan, Ahmed M Gharib

2 registry-linked trialsOpen access · greenAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Radiology. Cardiothoracic imaging, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01399385 narecruitingnot on this map

Magnetic Resonance of Body, Arterial Wall, and Angiography Imaging for Non- Invasive Assessment of Arterial Distensibility, Endothelial Dysfunction and Atherosclerotic Disease Using 1.5T and High Field (3T) MRI: A Technical Development Study of Cardiac and Body Imaging

TypeinterventionalSponsorNational Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)Ran2011 to 2030Enrolled4,000ConditionsHealthy, Obesity, Diabetes, Healthy VolunteersArmsMR Imaging Techniques - 1, MR Imaging Techniques - 2, MR Imaging Techniques - 3, MR Imaging Techniques - 4
NCT01656564 completednot on this map

Clinical Outcomes in Persons With HIV Acquired Early in Life

TypeobservationalSponsorNational Institute of Allergy and Infectious Diseases (NIAID)Ran2012 to 2023Enrolled177ConditionsHIV
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Radiology. Cardiothoracic imaging · 2025
    Review
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Khaled Z Abd-ElmoniemFrom the Biomedical and Metabolic Imaging Branch, National Institute of Diabetes and Digestive and Kidney Diseases (K.Z.A.E., H.I., J.M., A.H., A.M.G.), Critical Care Medicine Department, National Institutes of Health Clinical Center (J.P.), National Human Genome Research Institute (H.H.), and National Institute of Allergy and Infectious Diseases (C.H.), National Institutes of Health, 10 Center Dr, Bethesda, MD 20892; and Department of Radiology, University of Chicago, Chicago, Ill (A.H.).ORCID 0000-0002-1001-1702
Hadjira IshaqFrom the Biomedical and Metabolic Imaging Branch, National Institute of Diabetes and Digestive and Kidney Diseases (K.Z.A.E., H.I., J.M., A.H., A.M.G.), Critical Care Medicine Department, National Institutes of Health Clinical Center (J.P.), National Human Genome Research Institute (H.H.), and National Institute of Allergy and Infectious Diseases (C.H.), National Institutes of Health, 10 Center Dr, Bethesda, MD 20892; and Department of Radiology, University of Chicago, Chicago, Ill (A.H.).
Julia PurdyFrom the Biomedical and Metabolic Imaging Branch, National Institute of Diabetes and Digestive and Kidney Diseases (K.Z.A.E., H.I., J.M., A.H., A.M.G.), Critical Care Medicine Department, National Institutes of Health Clinical Center (J.P.), National Human Genome Research Institute (H.H.), and National Institute of Allergy and Infectious Diseases (C.H.), National Institutes of Health, 10 Center Dr, Bethesda, MD 20892; and Department of Radiology, University of Chicago, Chicago, Ill (A.H.).
Jatin MattaFrom the Biomedical and Metabolic Imaging Branch, National Institute of Diabetes and Digestive and Kidney Diseases (K.Z.A.E., H.I., J.M., A.H., A.M.G.), Critical Care Medicine Department, National Institutes of Health Clinical Center (J.P.), National Human Genome Research Institute (H.H.), and National Institute of Allergy and Infectious Diseases (C.H.), National Institutes of Health, 10 Center Dr, Bethesda, MD 20892; and Department of Radiology, University of Chicago, Chicago, Ill (A.H.).ORCID 0000-0001-6314-9409
Ahmed HamimiFrom the Biomedical and Metabolic Imaging Branch, National Institute of Diabetes and Digestive and Kidney Diseases (K.Z.A.E., H.I., J.M., A.H., A.M.G.), Critical Care Medicine Department, National Institutes of Health Clinical Center (J.P.), National Human Genome Research Institute (H.H.), and National Institute of Allergy and Infectious Diseases (C.H.), National Institutes of Health, 10 Center Dr, Bethesda, MD 20892; and Department of Radiology, University of Chicago, Chicago, Ill (A.H.).ORCID 0000-0001-6688-1937
Hwaida HannoushFrom the Biomedical and Metabolic Imaging Branch, National Institute of Diabetes and Digestive and Kidney Diseases (K.Z.A.E., H.I., J.M., A.H., A.M.G.), Critical Care Medicine Department, National Institutes of Health Clinical Center (J.P.), National Human Genome Research Institute (H.H.), and National Institute of Allergy and Infectious Diseases (C.H.), National Institutes of Health, 10 Center Dr, Bethesda, MD 20892; and Department of Radiology, University of Chicago, Chicago, Ill (A.H.).
Colleen HadiganFrom the Biomedical and Metabolic Imaging Branch, National Institute of Diabetes and Digestive and Kidney Diseases (K.Z.A.E., H.I., J.M., A.H., A.M.G.), Critical Care Medicine Department, National Institutes of Health Clinical Center (J.P.), National Human Genome Research Institute (H.H.), and National Institute of Allergy and Infectious Diseases (C.H.), National Institutes of Health, 10 Center Dr, Bethesda, MD 20892; and Department of Radiology, University of Chicago, Chicago, Ill (A.H.).ORCID 0000-0003-0642-7817
Ahmed M GharibFrom the Biomedical and Metabolic Imaging Branch, National Institute of Diabetes and Digestive and Kidney Diseases (K.Z.A.E., H.I., J.M., A.H., A.M.G.), Critical Care Medicine Department, National Institutes of Health Clinical Center (J.P.), National Human Genome Research Institute (H.H.), and National Institute of Allergy and Infectious Diseases (C.H.), National Institutes of Health, 10 Center Dr, Bethesda, MD 20892; and Department of Radiology, University of Chicago, Chicago, Ill (A.H.).ORCID 0000-0002-2476-481X
National Institute of Diabetes and Digestive and Kidney Diseases · USUniversity of Chicago · US

Funding

Advanced Non Invasive Vascular Imaging MethodsZIADK075083 · NIDDK · NATIONAL INSTITUTE OF DIABETES AND DIGESTIVE AND KIDNEY DISEASES · PI GHARIB, AHMED · 2013 to 2025
$34.7M
6 · The paper itself

Abstract

Purpose To assess early subclinical coronary artery disease (CAD) burden and its relation to myocardial function in asymptomatic persons living with HIV (PLWH) who are at low risk for cardiovascular disease (CVD). Materials and Methods In this prospective, HIPAA-compliant study (ClinicalTrials.gov NCT01656564 and NCT01399385) conducted from April 2010 to May 2013, 74 adult PLWH without known CVD and 25 matched healthy controls underwent coronary MRI to measure coronary vessel wall thickness (VWT) and echocardiography to assess left ventricular function. Univariable and multivariable linear regression analyses were used to evaluate statistical associations. Results For PLWH, the mean age was 49 years ± 11 (SD), and the median Framingham risk score was 3.2 (IQR, 0.5-6.6); for matched healthy controls, the mean age was 46 years ± 8 and Framingham risk score was 2.3 (IQR, 0.6-6.1). PLWH demonstrated significantly greater coronary artery VWT than did controls (1.47 mm ± 0.22 vs 1.34 mm ± 0.18;

Indexed as

Cardiovascular DiseasesHIV InfectionsAdultDiastoleHeartHumansMiddle AgedProspective StudiesAtherosclerosisCoronary Vessel Wall ThicknessDiastolic FunctionEchocardiographyHIVMRI

Identifiers

PMID38573125
PMCPMC11056756
OpenAlexW4393933129

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.