ArticleAnimal bioscience2024
Genome-wide association research on the reproductive traits of Qianhua Mutton Merino sheep.
Article in Animal bioscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 7 citations in OpenAlex.
- Association of Silent Variant p.17Pro = SNP in the LHX4 Gene with Litter Size in Awassi Sheep.Biochemical genetics · 2026Article
- Population structure, regions of homozygosity (ROH) and selection signal of two domesitic goat breeds revealed by whole-genome resequencing.BMC genomics · 2026Article
- Comparative DCMS analysis reveals a novel breed-specific X-linked selection signature in Changthangi sheep.Frontiers in genetics · 2026Article
- Genomic Characterization of Crossbred-Driven Adaptation in the Endangered Yangba Cattle of China.Animals : an open access journal from MDPI · 2025Article
- Transcriptome sequencing reveals the key genes associated with hair follicle development in Qianhua Mutton Merino.Frontiers in veterinary science · 2025Article
- Article
- Genetic Diversity, Selection Signatures, and Genome-Wide Association Study Identify Candidate Genes Related to Litter Size in Hu Sheep.International journal of molecular sciences · 2024Article
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
objectiveQianhua Mutton Merino sheep is a new breed of meat wool sheep cultivated independently in China. In 2018, it was approved by the state and brought into the national list of livestock and poultry genetic resources. Qianhua Mutton Merino sheep have the common characteristics of typical meat livestock varieties with rapid growth and development in the early stage and high meat production performance. The objective of this research is to investigate the Genome-wide association of the reproductive traits of Qianhua Mutton Merino sheep.
methodsQianhua Mutton Merino sheep from the breeding core group were selected as the research object, genome-wide association analysis was conducted on genes associated with the reproductive traits (singleton or twins, birth weight, age [in days] for sexual maturity, weaning weight, and daily gain from birth to weaning) of Qianhua mutton merino.
resultsOur study findings showed that 151 loci of single-nucleotide polymorphisms (SNPs) were detected, among which 3 SNPs related to birth weight and weaning weight occupied a significant portion of the wide genome. The candidate genes preliminarily obtained were SYNE1, SLC12A4, BMP2K, CAMK2D, IMMP2L, DMD, and BCL2.
conclusionWe found 151 SNP loci for five traits related to reproduction (including singleton or twins, birth weight, age [in days] at sexual maturity, weaning weight, and daily weight gain from birth to weaning). The functions of these candidate genes were mainly enriched in nucleotide metabolism, metal ion binding, oxytocin signaling pathway, and neurotrophin signaling pathway.
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