Evidence map›Paper›PMID 38575412›Full record

ReviewTrends in cancer2024

Label-free optical imaging for brain cancer assessment.

Raksha Raghunathan, Matthew Vasquez, Katherine Zhang, Hong Zhao, Stephen T C Wong

Open access · greenAbstract readReview
In one paragraph

Review in Trends in cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Advancements in nanotheranostics for glioma therapy.Naunyn-Schmiedeberg's archives of pharmacology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Raksha RaghunathanDepartment of Systems Medicine and Bioengineering and T.T. and W.F. Chao Center for BRAIN, Houston Methodist Neal Cancer Center, Houston Methodist Hospital, Houston, TX 77030, USA; Advanced Cellular and Tissue Microscopy Core, Houston Methodist Neal Cancer Center and Houston Methodist Research Institute, Houston, TX 77030, USA.
Matthew VasquezDepartment of Systems Medicine and Bioengineering and T.T. and W.F. Chao Center for BRAIN, Houston Methodist Neal Cancer Center, Houston Methodist Hospital, Houston, TX 77030, USA; Advanced Cellular and Tissue Microscopy Core, Houston Methodist Neal Cancer Center and Houston Methodist Research Institute, Houston, TX 77030, USA.
Katherine ZhangDepartment of Systems Medicine and Bioengineering and T.T. and W.F. Chao Center for BRAIN, Houston Methodist Neal Cancer Center, Houston Methodist Hospital, Houston, TX 77030, USA; Advanced Cellular and Tissue Microscopy Core, Houston Methodist Neal Cancer Center and Houston Methodist Research Institute, Houston, TX 77030, USA.
Hong ZhaoDepartment of Systems Medicine and Bioengineering and T.T. and W.F. Chao Center for BRAIN, Houston Methodist Neal Cancer Center, Houston Methodist Hospital, Houston, TX 77030, USA; Advanced Cellular and Tissue Microscopy Core, Houston Methodist Neal Cancer Center and Houston Methodist Research Institute, Houston, TX 77030, USA; Department of Medicine, Weill Cornell Medicine, New York, NY 10065, USA. Electronic address: HZhao@houstonmethodist.org.
Stephen T C WongDepartment of Systems Medicine and Bioengineering and T.T. and W.F. Chao Center for BRAIN, Houston Methodist Neal Cancer Center, Houston Methodist Hospital, Houston, TX 77030, USA; Advanced Cellular and Tissue Microscopy Core, Houston Methodist Neal Cancer Center and Houston Methodist Research Institute, Houston, TX 77030, USA; Departments of Radiology, Pathology, and Laboratory Medicine and Brain and Mind Research Institute, Weill Cornell Medicine, New York, NY 10065, USA.
Houston Methodist · US

Funding

Systematic identification of astrocyte-tumor crosstalk regulating brain metastatic tumorsR01CA238727 · NCI · METHODIST HOSPITAL RESEARCH INSTITUTE · PI WONG, STEPHEN TC, ZHAO, HONG · 2020 to 2024
$2.6M
NCI NIH HHS R01 CA238727
6 · The paper itself

Abstract

Advances in label-free optical imaging offer a promising avenue for brain cancer assessment, providing high-resolution, real-time insights without the need for radiation or exogeneous agents. These cost-effective and intricately detailed techniques overcome the limitations inherent in magnetic resonance imaging (MRI), computed tomography (CT), and positron emission tomography (PET) scans by offering superior resolution and more readily accessible imaging options. This comprehensive review explores a variety of such methods, including photoacoustic imaging (PAI), optical coherence tomography (OCT), Raman imaging, and IR microscopy. It focuses on their roles in the detection, diagnosis, and management of brain tumors. By highlighting recent advances in these imaging techniques, the review aims to underscore the importance of label-free optical imaging in enhancing early detection and refining therapeutic strategies for brain cancer.

Indexed as

Brain NeoplasmsPhotoacoustic TechniquesTomography, Optical CoherenceAnimalsHumansOptical ImagingSpectrum Analysis, Ramanbrain cancerIR microscopylabel-free optical imagingoptical coherence tomographyphotoacoustic imagingRaman imaging

Identifiers

PMID38575412
PMCPMC11168891
OpenAlexW4393944545

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.