Evidence map›Paper›PMID 38575862›Full record

ArticleBMC microbiology2024

Effect of stress urinary incontinence on vaginal microbial communities.

Man Zhang, Yanhua Zhou, Siqi Yao, Yiming Zhao, Syeda Sundas Batool, Jing Huang, Li Jiang, Dayu Yan, Wenguang Yan, Zheng Yu

Open access · goldAbstract read
In one paragraph

Article in BMC microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 6 citations in OpenAlex.

  1. Trial
  2. Article
  3. Inflammatory landscape ofFrontiers in immunology · 2026
    Article
  4. Article
  5. Article
  6. Ecological mechanisms of microbial assembly in clonal plantApplied and environmental microbiology · 2025
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Man Zhang *Human Microbiome and Health Group, Department of Microbiology, School of Basic Medical Science, Central South University, Changsha, Hunan, China.
Yanhua Zhou *Department of Rehabilitation Medicine, The Third Xiangya Hospital, Central South University, Changsha, China.
Siqi YaoHuman Microbiome and Health Group, Department of Microbiology, School of Basic Medical Science, Central South University, Changsha, Hunan, China.
Yiming ZhaoHuman Microbiome and Health Group, Department of Microbiology, School of Basic Medical Science, Central South University, Changsha, Hunan, China.
Syeda Sundas BatoolHuman Microbiome and Health Group, Department of Microbiology, School of Basic Medical Science, Central South University, Changsha, Hunan, China.
Jing HuangDepartment of Parasitology, School of Basic Medical Science, Central South University, Changsha, Hunan, China.
Li JiangDepartment of Rehabilitation Medicine, The Third Xiangya Hospital, Central South University, Changsha, China.
Dayu YanDepartment of Gynecology, The Third Xiangya Hospital, Central South University, Changsha, China.
Wenguang YanDepartment of Rehabilitation Medicine, The Third Xiangya Hospital, Central South University, Changsha, China. ywgpmn@csu.edu.cn.
Zheng YuHuman Microbiome and Health Group, Department of Microbiology, School of Basic Medical Science, Central South University, Changsha, Hunan, China. yuzheng@csu.edu.cn.
Central South University · CNThird Xiangya Hospital · CN

Funding

National Natural Science Foundation of China 32000054 and 32170071
6 · The paper itself

Abstract

backgroundPostpartum women often experience stress urinary incontinence (SUI) and vaginal microbial dysbiosis, which seriously affect women's physical and mental health. Understanding the relationship between SUI and vaginal microbiota composition may help to prevent vaginal diseases, but research on the potential association between these conditions is limited.

resultsThis study employed 16S rRNA gene sequencing to explore the association between SUI and vaginal dysbiosis. In terms of the vaginal microbiota, both species richness and evenness were significantly higher in the SUI group. Additionally, the results of NMDS and species composition indicated that there were differences in the composition of the vaginal microbiota between the two groups. Specifically, compared to postpartum women without SUI (Non-SUI), the relative abundance of bacteria associated with bacterial dysbiosis, such as Streptococcus, Prevotella, Dialister, and Veillonella, showed an increase, while the relative abundance of Lactobacillus decreased in SUI patients. Furthermore, the vaginal microbial co-occurrence network of SUI patients displayed higher connectivity, complexity, and clustering.

conclusionThe study highlights the role of Lactobacillus in maintaining vaginal microbial homeostasis. It found a correlation between SUI and vaginal microbiota, indicating an increased risk of vaginal dysbiosis. The findings could enhance our understanding of the relationship between SUI and vaginal dysbiosis in postpartum women, providing valuable insights for preventing bacterial vaginal diseases and improving women's health.

Indexed as

MicrobiotaUrinary Incontinence, StressVaginal DiseasesBacteriaDysbiosisFemaleHumansLactobacillusRNA, Ribosomal, 16SVaginaRNA, Ribosomal, 16SDysbiosisLactobacillusStress urinary incontinenceVaginal microbiota

Identifiers

PMID38575862
PMCPMC10993610
OpenAlexW4393947185

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.