Evidence map›Paper›PMID 38575887›Full record

Trial reportBMC primary care2024

Low-value chronic prescription of acid reducing medication among Dutch general practitioners: impact of a patient education intervention.

Joris L J M Müskens, Simone A van Dulmen, Karin Hek, Gert P Westert, Rudolf B Kool

Registry-linked trialOpen access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC primary care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06108817 (Low-value Chronic Prescription of Acid Reducing Medication Among Dutch General Practitioners), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06108817 nacompletednot on this map

Low-value Chronic Prescription of Acid Reducing Medication Among Dutch General Practitioners: Impact of a Patient Education Intervention

TypeinterventionalSponsorRadboud University Medical CenterRan2022 to 2023Enrolled26ConditionsDyspepsiaArmsInformation material, No Intervention
3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Joris L J M MüskensIQ Health Science Department, Radboud University Medical Center, Research Institute for Medical Innovation, Nijmegen, The Netherlands. joris.muskens@radboudumc.nl.
Simone A van DulmenIQ Health Science Department, Radboud University Medical Center, Research Institute for Medical Innovation, Nijmegen, The Netherlands.
Karin HekNivel, Netherlands Institute for Health Services Research, Utrecht, The Netherlands.
Gert P WestertIQ Health Science Department, Radboud University Medical Center, Research Institute for Medical Innovation, Nijmegen, The Netherlands.
Rudolf B KoolIQ Health Science Department, Radboud University Medical Center, Research Institute for Medical Innovation, Nijmegen, The Netherlands.
Radboud University Medical Center · NLNetherlands Institute for Health Services Research · NLRadboud University Nijmegen · NL

Funding

ZonMw 839205002
6 · The paper itself

Abstract

backgroundDyspepsia is a commonly encountered clinical condition in Dutch general practice, which is often treated through the prescription of acid-reducing medication (ARM). However, recent studies indicate that the majority of chronic ARM users lack an indication for their use and that their long-term use is associated with adverse outcomes. We developed a patient-focussed educational intervention aiming to reduce low-value (chronic) use of ARM.

methodsWe conducted a randomized controlled study, and evaluated its effect on the low-value chronic prescription of ARM using data from a subset (n = 26) of practices from the Nivel Primary Care Database. The intervention involved distributing an educational waiting room posters and flyers informing both patients and general practitioners (GPs) regarding the appropriate indications for prescription of an ARM for dyspepsia, which also referred to an online decision aid. The interventions' effect was evaluated through calculation of the odds ratio of a patient receiving a low-value chronic ARM prescription over the second half of 2021 and 2022 (i.e. pre-intervention vs. post-intervention).

resultsIn both the control and intervention groups, the proportion of patients receiving chronic low-value ARM prescriptions slightly increased. In the control group, it decreased from 50.3% in 2021 to 49.7% in 2022, and in the intervention group it increased from 51.3% in 2021 to 53.1% in 2022. Subsequent statistical analysis revealed no significant difference in low-value chronic prescriptions between the control and intervention groups (Odds ratio: 1.11 [0.84-1.47], p > 0.05).

conclusionOur educational intervention did not result in a change in the low-value chronic prescription of ARM; approximately half of the patients of the intervention and control still received low-value chronic ARM prescriptions. The absence of effect might be explained by selection bias of participating practices, awareness on the topic of chronic AMR prescriptions and the relative low proportion of low-value chronic ARM prescribing in the intervention as well as the control group compared to an assessment conducted two years prior.

trial registration10/31/2023 NCT06108817.

Indexed as

DyspepsiaGeneral PracticeGeneral PractitionersDrug PrescriptionsEuropean PeopleHumansNetherlandsPatient Education as TopicAcid reducing medicationDyspepsiaGeneral practiceLow-value carePatient decision aid

Identifiers

PMID38575887
PMCPMC10996147
OpenAlexW4393952405

What Socratic holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.