Evidence mapPaperPMID 38580913Full record

Trial reportBMC neurology2024

Feasibility of a novel eHealth intervention for Parkinson's disease targeting motor-cognitive function in the home.

Jenny Sedhed, Hanna Johansson, Nina Andersson, Elisabet Åkesson, Elke Kalbe, Erika Franzén, Breiffni Leavy

Registry-linked trialOpen access · goldAbstract readClinical Trial
In one paragraph

Trial report in BMC neurology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05027620 (Continued Support for Physical Activity in Everyday Life With Parkinson's Disease Using eHealth Technology), which is not on this map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05027620 nacompletednot on this map

Continued Support for Physical Activity in Everyday Life With Parkinson's Disease Using eHealth Technology

TypeinterventionalSponsorStiftelsen Stockholms SjukhemRan2021 to 2022Enrolled15ConditionsIdiopathic Parkinson Disease, Telerehabilitation, Physical TherapyArmsMotor-cognitive exercise therapy in the home
3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Digital Inclusion in Parkinson's Disease: A Case-Control Study.Movement disorders clinical practice · 2025
    Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 3 countries.

Jenny SedhedStockholm Sjukhem Foundation, R&D unit, Stockholm, Sweden. jenny.sedhed@ki.se.
Hanna JohanssonStockholm Sjukhem Foundation, R&D unit, Stockholm, Sweden.
Nina AnderssonStockholm Sjukhem Foundation, R&D unit, Stockholm, Sweden.
Elisabet ÅkessonStockholm Sjukhem Foundation, R&D unit, Stockholm, Sweden.
Elke KalbeMedical Psychology | Neuropsychology and Gender Studies and Center for Neuropsychological Diagnostics and Intervention (CeNDI), Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany.
Erika FranzénStockholm Sjukhem Foundation, R&D unit, Stockholm, Sweden.
Breiffni LeavyStockholm Sjukhem Foundation, R&D unit, Stockholm, Sweden.
Swedish Foundation for Strategic Research · SEKarolinska University Hospital · SEKarolinska Institutet · SEUniversity of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundParkinson's disease (PD) drastically affects motor and cognitive function, but evidence shows that motor-cognitive training improves disease symptoms. Motor-cognitive training in the home is scarcely investigated and eHealth methods can provide continual support for PD self-management. Feasibility testing is however required.

objectiveTo assess the feasibility (i) Recruitment capability (ii) Acceptability and Suitability (iii) Demand and Safety of a home-based motor-cognitive eHealth exercise intervention in PD.

methodsThe 10-week intervention was delivered using the ExorLive® application and exercises were individually adapted and systematically progressed and targeted functional strength, cardiovascular fitness, flexibility, and motor-cognitive function. People with mild-to moderate PD were assessed before and after the intervention regarding; gait performance in single and dual-task conditions; functional mobility; dual-task performance; balance performance; physical activity level; health related quality of life and perceived balance confidence and walking ability; global cognition and executive function. Feasibility outcomes were continuously measured using a home-exercise diary and contact with a physiotherapist. Changes from pre- and post-intervention are reported descriptively.

resultsFifteen participants (mean age 68.5 years) commenced and 14 completed the 10-week intervention. In relation to intervention Acceptability, 64% of the motor sessions and 52% of motor-cognitive sessions were rated as "enjoyable". Concerning Suitability, the average level of exertion (Borg RPE scale) was light (11-12). Adherence was high, with 86% of all (420) sessions reported as completed. No falls or other adverse events occurred in conjunction with the intervention.

conclusionsThis motor-cognitive eHealth home exercise intervention for PD was safe and feasible in terms of Recruitment capability, Acceptability, Safety and Demand. The intensity of physical challenge needs to be increased before testing in an efficacy trial.

trial registrationThis trial is registered at Clinicaltrials.gov (NCT05027620).

Indexed as

Parkinson DiseaseTelemedicineAgedCognitionExercise TherapyFeasibility StudiesHumansQuality of LifeCognitioneHealthExerciseMotor-cognitive exerciseParkinson’s disease

Identifiers

PMID38580913
PMCPMC10996106
OpenAlexW4393989010

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.