Evidence map›Paper›PMID 38581012›Full record

ArticleCell communication and signaling : CCS2024

Inhibition of adenylyl cyclase by GTPase-deficient Gα

Yin Kwan Chung, Ho Yung Chan, Tung Yeung Lee, Yung Hou Wong

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Cell communication and signaling : CCS, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Yin Kwan Chung *Division of Life Science and Biotechnology Research Institute, Hong Kong University of Science and Technology, Hong Kong, China.
Ho Yung Chan *Division of Life Science and Biotechnology Research Institute, Hong Kong University of Science and Technology, Hong Kong, China.
Tung Yeung LeeDivision of Life Science and Biotechnology Research Institute, Hong Kong University of Science and Technology, Hong Kong, China.
Yung Hou WongDivision of Life Science and Biotechnology Research Institute, Hong Kong University of Science and Technology, Hong Kong, China. boyung@ust.hk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Signal transduction through G protein-coupled receptors (GPCRs) has been a major focus in cell biology for decades. Numerous disorders are associated with GPCRs that utilize G

Indexed as

Adenylyl CyclasesGTP PhosphohydrolasesCarrier ProteinsGTP-Binding Protein alpha Subunits, Gi-GoGTP-Binding ProteinsMolecular Docking SimulationAdenylyl CyclasesCarrier ProteinsGTP-Binding Protein alpha Subunits, Gi-GoGTP-Binding ProteinsGTP PhosphohydrolasesAC inhibitionConstitutively active mutantsEffector recognition domainG protein-coupled receptorReceptor activation

Identifiers

PMID38581012
PMCPMC10996109

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.