Evidence mapPaperPMID 38584607Full record

ArticleAmerican journal of preventive cardiology2024

Epicardial and intra-thoracic adipose tissue and cardiovascular calcifications in type 1 diabetes (T1D) in epidemiology of diabetes Interventions and Complications (EDIC): A pilot study.

Panteha Rezaeian, Jye-Yu C Backlund, Mohammed Zaveri, Rine Nakanishi, Suguru Matsumoto, Anas Alani, Aryabod Razipour, John M Lachin, Matthew Budoff, DCCT/EDIC Research Group

Abstract read
In one paragraph

Article in American journal of preventive cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Panteha RezaeianTorrance Memorial Physician Network-Cedars-Sinai Health System affiliate, Torrance, CA, USA.
Jye-Yu C BacklundThe Biostatistics Center, George Washington University, Rockville, MD, USA.
Mohammed ZaveriDepartment of Medicine Emanate Health Medical Group, West Covina, CA, USA.
Rine NakanishiDepartment of Cardiovascular Medicine, Toho University Graduate School of Medicine, Tokyo, Japan.
Suguru MatsumotoDepartment of Cardiology, Kouiki Monbetsu Hospital, Hokkaido, Japan.
Anas AlaniDepartment of Cardiology, University of Loma Linda, Loma Linda, CA, USA.
Aryabod RazipourBiomedical Imaging Research Institute, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
John M LachinThe Biostatistics Center, George Washington University, Rockville, MD, USA.
Matthew BudoffLindquist Research Institute, Harbor-UCLA Medical Center, 1124W Carson St, Torrance, CA 90502, USA.
DCCT/EDIC Research Group

Funding

Clinical and Translational Science CenterUL1TR002384 · WEILL MEDICAL COLL OF CORNELL UNIV · 2025 to 2025
$9.8M
Epidemiology of Diabetes Interventions and Complications (EDIC) StudyU01DK094157 · CASE WESTERN RESERVE UNIVERSITY · 2025 to 2025
$8.0M
NCATS NIH HHS UL1 TR002384NIDDK NIH HHS U01 DK094157
6 · The paper itself

Abstract

Objective: Coronary artery, aortic valve, and descending aorta calcification (CAC, AVC, DAC) are manifestations of atherosclerosis, and cardiac epicardial adipose tissue (EAT) indicates heart adiposity. This study explored the association between cardiac adipose tissue and cardiovascular calcification in participants with long-standing T1D. Methods: EAT and intra-thoracic adipose tissue (IAT) were measured in 100 T1D subjects with cardiac computed tomography (CT) scans in the EDIC study. Volume analysis software was used to measure fat volumes. Spearman correlations were calculated between CAC, AVC, DAC with EAT, and IAT. Associations were evaluated using multiple linear and logistic regression models. Results: Participants ranged in age from 32 to 57. Mean EAT, and IAT were 38.5 and 50.8 mm Conclusion: In participants with T1D, higher EAT and IAT levels are correlated with higher CAC scores. EAT and IAT were not independently correlated with DAC or AVC.

Indexed as

Adipose tissueCalcificationCoronaryEpicardialIntra-thoracicType 1 Diabtes Melitus

Identifiers

PMID38584607
PMCPMC10995972

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.