Evidence map›Paper›PMID 38585263›Full record

ReviewFrontiers in immunology2024

Facial palsy after administration of immune checkpoint inhibitors: case report, literature review and clinical care management.

Essia Mezni, Giovanni Corazza, Roxane Mari, Stephanie Coze, Nathalie Charrier, Brice Chanez, Anne Sophie Chretien, Philippe Rochigneux

Open access · goldAbstract readReviewCase Reports
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Essia MezniMedical Oncology Department, Paoli-Calmettes Institute, Marseille, France.
Giovanni CorazzaNeurology Department, Assitance Publique Hôpitaux de Marseille, Aix-Marseille University, Marseille, France.
Roxane MariMedical Oncology Department, Paoli-Calmettes Institute, Marseille, France.
Stephanie CozeRadiology Department, Assitance Publique Hôpitaux de Marseille, Aix-Marseille University, Marseille, France.
Nathalie CharrierNuclear Medicine Department, Paoli-Calmettes Institut, Marseille, France.
Brice ChanezMedical Oncology Department, Paoli-Calmettes Institute, Marseille, France.
Anne Sophie ChretienTeam Immunity and Cancer, Centre de Recherche en Canceírologie de Marseille (CRCM), Inserm, U1068, Centre national de la recherche scientifique (CNRS), Unité Mixte de Recherche 7258 (UMR7258), Paoli-Calmettes Institute, Aix-Marseille University, Marseille, France.
Philippe RochigneuxMedical Oncology Department, Paoli-Calmettes Institute, Marseille, France.
Institut Paoli-Calmettes · FRAix-Marseille Université · FRCentre National de la Recherche Scientifique · FRHôpital de la Timone · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurological immune-related adverse events (irAEs) due to immune checkpoint inhibitors (ICI) are rare complications of immunotherapy, particularly dreadful for patients and clinical teams. Indeed, neurological irAEs are potentially severe and their diagnosis require prompt recognition and treatment. Additionally, the spectrum of neurological irAEs is broad, affecting either neuromuscular junction, peripheral or central nervous system. Here, we described the case of a 55-year man with metastatic melanoma, facing a brutal right peripheral cerebral palsy after his third ipilimumab/nivolumab infusion. After the case presentation, we reviewed the literature about this rare complication of immunotherapy, and described its diagnosis work-up and clinical management.

Indexed as

Facial ParalysisMelanomaHumansImmune Checkpoint InhibitorsIpilimumabMaleNivolumabImmune Checkpoint InhibitorsIpilimumabNivolumabcerebral palsyimmune checkpoint inhibitorsimmune toxicityipilimumabneurological toxicitynivolumab

Identifiers

PMID38585263
PMCPMC10995231
OpenAlexW4393094747

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.