Evidence map›Paper›PMID 38589521›Full record

ArticleScientific reports2024

Analyzing the changing trend of corneal biomechanical properties under different influencing factors in T2DM patients.

Juan Tang, Zhiwu Lin, Xingde Liu, Biao Li, Xiaoli Wu, Jing Lv, Xing Qi, Sheng Lin, Chuanqiang Dai, Tao Li

Abstract read
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Juan Tang *Department of Endocrinology, Ziyang Central Hospital, Sichuan, China.
Zhiwu Lin *Department of Cardiothoracic Surgery, Ziyang Central Hospital, Sichuan, China.
Xingde LiuDepartment of Ophthalmology, Ziyang Central Hospital, Sichuan, China.
Biao LiDepartment of Ophthalmology, Ziyang Central Hospital, Sichuan, China.
Xiaoli WuDepartment of Ophthalmology, Ziyang Central Hospital, Sichuan, China.
Jing LvDepartment of Orthopedics, Ziyang Central Hospital, Sichuan, China.
Xing QiDepartment of Experimental Medicine, Ziyang Central Hospital, Sichuan, China.
Sheng LinDepartment of Experimental Medicine, Ziyang Central Hospital, Sichuan, China.
Chuanqiang DaiDepartment of Orthopedics, Ziyang Central Hospital, Sichuan, China. 59490003@qq.com.
Tao LiDepartment of Ophthalmology, Ziyang Central Hospital, Sichuan, China. m18203005640@163.com.

Funding

2022 Key Projects of Sichuan Provincial Science and Technology Plan 2022YFS01522023 Ziyang Science and Technology Bureau Project zykjjsc20-yyjc-2023-042023 Ziyang Science and Technology Bureau Project zykjjsc20-yyjc-2023-352024 Hebei Province Medical Science Research Project Plan 20240294Ziyang City Medical Science Project KY2023001Ziyang City Medical Science Project KY2023022
6 · The paper itself

Abstract

To analyze the changing trend of CH and CRF values under different influencing factors in T2DM patients. A total of 650 patients with T2DM were included. We discovered that the course of T2DM, smoking history, BMI, and FBG, DR, HbA1c, TC, TG, and LDL-C levels were common risk factors for T2DM, while HDL-C levels were a protective factor. Analyzing the CH and CRF values according to the course of diabetes, we discovered that as T2DM continued to persist, the values of CH and CRF gradually decreased. Moreover, with the increase in FBG levels and the accumulation of HbA1c, the values of CH and CRF gradually decreased. In addition, in patients with HbA1c (%) > 12, the values of CH and CRF decreased the most, falling by 1.85 ± 0.33 mmHg and 1.28 ± 0.69 mmHg, respectively. Compared with the non-DR group, the CH and CRF values gradually decreased in the mild-NPDR, moderate-NPDR, severe-NPDR and PDR groups, with the lowest CH and CRF values in the PDR group. In patients with T2DM, early measurement of corneal biomechanical properties to evaluate the change trend of CH and CRF values in different situations will help to identify and prevent diabetic keratopathy in a timely manner.

Indexed as

CorneaDiabetes Mellitus, Type 2Biomechanical PhenomenaElasticityGlycated HemoglobinHumansIntraocular PressureTonometry, OcularGlycated HemoglobinCorneal hysteresisCorneal resistance factorDiabetic keratopathyOcular response analyzerT2DM

Identifiers

PMID38589521
PMCPMC11001873

What Socratic holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.