ArticleNature immunology2024
Large-scale phenotyping of patients with long COVID post-hospitalization reveals mechanistic subtypes of disease.
Open access · hybridAbstract read
In one paragraph
Article in Nature immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 68 papers.
0numbers the graph read from it
0cells of the map it votes in
68citing papers in PubMed
31.7field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
68 citing papers in PubMed, 86 citations in OpenAlex.
- Integrated care pathway in individuals with Long COVID: STIMULATE-ICP, a cluster-randomized, phase 3 trial.Nature medicine · 2026Trial
- Tetrahydrocurcumin for Major Depressive Disorder with Therapeutic Potential and Mechanistic Insights from Clinical and Preclinical Studies.Molecular neurobiology · 2025Trial
- Cost-effectiveness of the ReDIRECT/counterweight-plus weight management programme to alleviate symptoms of long COVID.Nature communications · 2025Trial
- Pre-pandemic care-seeking patterns and subsequent diagnoses of post-COVID condition, post viral fatigue syndrome, and exhaustion disorder: a registry-based cohort study of 208,050 Swedish women.Scandinavian journal of primary health care · 2026Article
- Long-term ocular symptoms following COVID-19 linked to immune dysregulation, dysautonomia and peripheral neuropathy.Nature communications · 2026Article
- Self-management of long COVID symptoms with over-the-counter medicines and other non-prescribed therapies: a cross-sectional survey.BMC public health · 2026Article
- Current status and future perspectives on the mechanistic and pathophysiological understanding of long COVID.Communications medicine · 2026Article
- Distinct plasma proteome signature at 3 months post-COVID-19 infection irrespective of post-COVID condition.Scientific reports · 2026Article
- Divergent inflammatory and neurology-related protein levels in long COVID following primary and breakthrough SARS-CoV-2 infections.Communications medicine · 2026Article
- Computational proteomics to enhance personalized treatment of COVID-19 and Long COVID.Clinical proteomics · 2026Review
- Complement System Dysregulation in the Immunopathogenesis of Long COVID: Systematic Evidence Synthesis.Biomedicines · 2026Review
- A distinct monocyte transcriptional state links systemic immune dysregulation to pulmonary impairment in long COVID.Nature immunology · 2026Article
- Long-term sex differences in symptoms and immune profile in long COVID.Biology of sex differences · 2026Article
- Case Report: Post-mortem analysis of long-term inflammation after mild COVID-19.Frontiers in immunology · 2026Article
- CD4Frontiers in immunology · 2026Article
- Peripheral blood cytokines during early and post-acute stages of SARS-CoV-2 infection are associated with disease severity and long-term symptoms.Frontiers in immunology · 2026Article
- Plasma proteomic profile reveals persistent immune activation in post-acute sequelae of SARS-CoV-2 infection.Frontiers in immunology · 2026Article
- Inflammation and iron metabolism dysregulation as hallmarks of COVID-19 severity.Frontiers in immunology · 2026Observational
- The trigger-timing framework for long COVID: using symptom triggers and temporal patterns to guide mechanistic stratification and treatment planning.Frontiers in medicine · 2026Article
- Long COVID involves activation of proinflammatory and immune exhaustion pathways.Nature immunology · 2026Observational
8 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
51 authors at 20 institutions in 5 countries.
Felicity Liew *National Heart and Lung Institute, Imperial College London, London, UK.
Claudia Efstathiou *National Heart and Lung Institute, Imperial College London, London, UK.ORCID http://orcid.org/0000-0001-6125-8126
Sara FontanellaNational Heart and Lung Institute, Imperial College London, London, UK.
Matthew RichardsonInstitute for Lung Health, Leicester NIHR Biomedical Research Centre, University of Leicester, Leicester, UK.
Ruth SaundersInstitute for Lung Health, Leicester NIHR Biomedical Research Centre, University of Leicester, Leicester, UK.
Dawid SwiebodaNational Heart and Lung Institute, Imperial College London, London, UK.
Jasmin K SidhuNational Heart and Lung Institute, Imperial College London, London, UK.
Stephanie AscoughNational Heart and Lung Institute, Imperial College London, London, UK.
Shona C MooreNIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.ORCID http://orcid.org/0000-0001-8610-2806
Noura MohamedThe Imperial Clinical Respiratory Research Unit, Imperial College NHS Trust, London, UK.
Jose NunagCardiovascular Research Team, Imperial College Healthcare NHS Trust, London, UK.ORCID http://orcid.org/0000-0002-4218-0500
Clara KingCardiovascular Research Team, Imperial College Healthcare NHS Trust, London, UK.
Olivia C LeavyInstitute for Lung Health, Leicester NIHR Biomedical Research Centre, University of Leicester, Leicester, UK.
Omer ElneimaInstitute for Lung Health, Leicester NIHR Biomedical Research Centre, University of Leicester, Leicester, UK.
Hamish J C McAuleyInstitute for Lung Health, Leicester NIHR Biomedical Research Centre, University of Leicester, Leicester, UK.
Aarti ShikotraNIHR Leicester Biomedical Research Centre, University of Leicester, Leicester, UK.
Amisha SingapuriInstitute for Lung Health, Leicester NIHR Biomedical Research Centre, University of Leicester, Leicester, UK.ORCID http://orcid.org/0009-0002-4711-7516
Marco SerenoInstitute for Lung Health, Leicester NIHR Biomedical Research Centre, University of Leicester, Leicester, UK.ORCID http://orcid.org/0000-0003-4573-9303
Victoria C HarrisInstitute for Lung Health, Leicester NIHR Biomedical Research Centre, University of Leicester, Leicester, UK.
Linzy Houchen-WolloffCentre for Exercise and Rehabilitation Science, NIHR Leicester Biomedical Research Centre-Respiratory, University of Leicester, Leicester, UK.ORCID http://orcid.org/0000-0003-4940-8835
Neil J GreeningInstitute for Lung Health, Leicester NIHR Biomedical Research Centre, University of Leicester, Leicester, UK.ORCID http://orcid.org/0000-0003-0453-7529
Nazir I LoneUsher Institute, University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0003-2707-2779
Matthew ThorpeCentre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.
A A Roger ThompsonDepartment of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK.ORCID http://orcid.org/0000-0002-0717-4551
Sarah L Rowland-JonesDepartment of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK.
Annemarie B DochertyCentre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0001-8277-420X
James D ChalmersUniversity of Dundee, Ninewells Hospital and Medical School, Dundee, UK.
Ling-Pei HoMRC Human Immunology Unit, University of Oxford, Oxford, UK.ORCID http://orcid.org/0000-0001-8319-301X
Alexander HorsleyDivision of Infection, Immunity and Respiratory Medicine, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.ORCID http://orcid.org/0000-0003-1828-0058
Betty RamanRadcliffe Department of Medicine, University of Oxford, Oxford, UK.
Krisnah PoinasamyAsthma + Lung UK, London, UK.
Michael MarksDepartment of Clinical Research, London School of Hygiene and Tropical Medicine, London, UK.
Onn Min KonNational Heart and Lung Institute, Imperial College London, London, UK.
Luke S HowardNational Heart and Lung Institute, Imperial College London, London, UK.ORCID http://orcid.org/0000-0003-2822-210X
Daniel G WoottonNIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
Jennifer K QuintNational Heart and Lung Institute, Imperial College London, London, UK.
Thushan I de SilvaDepartment of Infection, Immunity and Cardiovascular Disease, University of Sheffield, Sheffield, UK.ORCID http://orcid.org/0000-0002-6498-9212
Antonia HoMRC Centre for Virus Research, School of Infection and Immunity, University of Glasgow, Glasgow, UK.
Christopher ChiuNational Heart and Lung Institute, Imperial College London, London, UK.ORCID http://orcid.org/0000-0003-0914-920X
Ewen M HarrisonCentre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0002-5018-3066
William GreenhalfInstitute of Systems, Molecular and Integrative Biology, University of Liverpool, Liverpool, UK.
J Kenneth BaillieCentre for Medical Informatics, The Usher Institute, University of Edinburgh, Edinburgh, UK.ORCID http://orcid.org/0000-0001-5258-793X
Malcolm G SempleNIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.ORCID http://orcid.org/0000-0001-9700-0418
Lance TurtleNIHR Health Protection Research Unit in Emerging and Zoonotic Infections, Institute of Infection, Veterinary and Ecological Sciences, University of Liverpool, Liverpool, UK.
Rachael A EvansInstitute for Lung Health, Leicester NIHR Biomedical Research Centre, University of Leicester, Leicester, UK.ORCID http://orcid.org/0000-0002-1667-868X
Louise V WainInstitute for Lung Health, Leicester NIHR Biomedical Research Centre, University of Leicester, Leicester, UK.
Christopher BrightlingInstitute for Lung Health, Leicester NIHR Biomedical Research Centre, University of Leicester, Leicester, UK.
Ryan S Thwaites *National Heart and Lung Institute, Imperial College London, London, UK. r.thwaites@imperial.ac.uk.ORCID http://orcid.org/0000-0003-3052-2793
Peter J M Openshaw *National Heart and Lung Institute, Imperial College London, London, UK. p.openshaw@imperial.ac.uk.ORCID http://orcid.org/0000-0002-7220-2555
PHOSP-COVID collaborative group
ISARIC investigators
University of Liverpool · GBUniversity of Leicester · GBUniversity Hospitals Birmingham NHS Foundation Trust · GBImperial College Healthcare NHS Trust · GBUniversity of Oxford · GBUniversity of Leeds · GBUniversity College Hospital · GBKing's College London · GBGuy's and St Thomas' NHS Foundation Trust · GBNottingham University Hospitals NHS Trust · GBSheffield Teaching Hospitals NHS Foundation Trust · GBUniversity of Cambridge · GBBetsi Cadwaladr University Health Board · GBUniversity of Nottingham · GBSherwood Forest Hospitals NHS Foundation Trust · GBNewcastle upon Tyne Hospitals NHS Foundation Trust · GBNorth Bristol NHS Trust · GBCardiff and Vale University Health Board · GBNHS Greater Glasgow and Clyde · GBRoslin Institute · GB
Funding
Medical Research Council MC_PC_19025Medical Research Council MC_PC_19059Medical Research Council MC_PC_20004Medical Research Council MC_PC_20029Medical Research Council MC_PC_20058Medical Research Council MC_UU_12014/12Medical Research Council MR/R005982/1Medical Research Council MR/R502121/1Medical Research Council MR/T50256X/1Medical Research Council MR/V027859/1Wellcome Trust
Abstract
One in ten severe acute respiratory syndrome coronavirus 2 infections result in prolonged symptoms termed long coronavirus disease (COVID), yet disease phenotypes and mechanisms are poorly understood
Indexed as
Biomedical ResearchCOVID-19HospitalizationHumansImmunoglobulin GPost-Acute COVID-19 SyndromeImmunoglobulin G
Identifiers
What Socratic holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.