Metformin × all-cause mortality

SynthesisAmerican journal of cardiovascular drugs : drugs, devices, and other interventions2024

Evaluation of the Lifetime Benefits of Metformin and SGLT2 Inhibitors in Type 2 Diabetes Mellitus Patients with Cardiovascular Disease: A Systematic Review and Two-Stage Meta-Analysis.

Hon Jen Wong et al.PubMed ↗Publisher ↗

What the trial testedas reported · 2024

Not counted

Probably increased deaths

+31%+10% to +55%

Bigger than 7 in 10 for all-cause mortality

As reported

HR 1.308, 95% CI 1.10–1.55 · the paper's word: All-cause mortality

One number in the abstract

the abstract, start to end

higher all-cause mortality (hazard ratio 1.308, 95% confidence interval

← favours treatmentfavours comparator →
could be chance
All-cause mortality
HR 1.3081.10–1.55
MetforminSGLT2 inhibitorsAll-cause mortality
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3 papers cite it

2024
2025
2026
this papercites it
Full record →Abstract, authors, funding and every citing paper · PMID 38589722