Evidence map›Paper›PMID 38590439›Full record

ArticleFrontiers in cellular and infection microbiology2024

Identification of kinase modulators as host-directed therapeutics against intracellular methicillin-resistant

Robin H G A van den Biggelaar, Kimberley V Walburg, Susan J F van den Eeden, Cassandra L R van Doorn, Eugenia Meiler, Alex S de Ries, Annemarie H Meijer, Tom H M Ottenhoff, Anno Saris

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Robin H G A van den BiggelaarLeiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Kimberley V WalburgLeiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Susan J F van den EedenLeiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Cassandra L R van DoornLeiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Eugenia MeilerGlobal Health Medicines R&D, GlaxoSmithKline, Tres Cantos, Spain.
Alex S de RiesInstitute of Biology Leiden, Leiden University, Leiden, Netherlands.
Annemarie H MeijerInstitute of Biology Leiden, Leiden University, Leiden, Netherlands.
Tom H M OttenhoffLeiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Anno SarisLeiden University Center for Infectious Diseases, Leiden University Medical Center, Leiden, Netherlands.
Leiden University Medical Center · NLLeiden University · NLGlaxoSmithKline (Spain) · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The increasing prevalence of antimicrobial-resistant

Indexed as

Methicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsAnimalsAnti-Bacterial AgentsHumansMicrobial Sensitivity TestsStaphylococcus aureusZebrafishAnti-Bacterial AgentsAMPKautophagyEGFR/HER kinase familyhost-directed therapyintracellular infectionmethicillin-resistant Staphylococcus aureuspublished kinase inhibitor set (PKIS)zebrafish embryo

Identifiers

PMID38590439
PMCPMC10999543
OpenAlexW4393156626

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.