Evidence map›Paper›PMID 38596207›Full record

ArticleCureus2024

Ketamine Infusion in a Resistant Obsessive-Compulsive Disorder Patient in Bangladesh with Severe Suicidal Ideation: A Case Report.

Sultana Algin, Debasish Banik, Sm Atikur Rahman, Saiful Mahmud Tusher, Fatema Tuj Johora, Asha Akter, Tanbir Ahmed, Md Abdul Monib Biswas, Susmita Sinha, Mainul Haque

Open access · diamondAbstract readCase Reports
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 1 institution in 3 countries.

Sultana AlginPsychiatry, Bangabandhu Sheikh Mujib Medical University, Dhaka, BGD.
Debasish BanikAnesthesia, Analgesia, and Intensive Care Medicine, Bangabandhu Sheikh Mujib Medical University, Dhaka, BGD.
Sm Atikur RahmanPsychiatry, Bangabandhu Sheikh Mujib Medical University, Dhaka, BGD.
Saiful Mahmud TusherAnesthesia, Analgesia, and Intensive Care Medicine, Bangabandhu Sheikh Mujib Medical University, Dhaka, BGD.
Fatema Tuj JohoraChild and Adolescent Psychiatry, Bangabandhu Sheikh Mujib Medical University, Dhaka, BGD.
Asha AkterPsychiatry, Bangabandhu Sheikh Mujib Medical University, Dhaka, BGD.
Tanbir AhmedChild and Adolescent Psychiatry, Bangabandhu Sheikh Mujib Medical University, Dhaka, BGD.
Md Abdul Monib BiswasPsychiatry, Bangabandhu Sheikh Mujib Medical University, Dhaka, BGD.
Susmita SinhaPhysiology, Khulna City Medical College and Hospital, Khulna, BGD.
Mainul HaqueKarnavati Scientific Research Center (KSRC), School of Dentistry, Karnavati University, Gandhinagar, IND.
Bangladesh Medical University · BD

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Treatment of resistant obsessive-compulsive disorder (OCD) typically results in insufficient symptom alleviation, and even long-term medication often fails to have the intended effect. Ketamine is a potent non-competitive antagonist of the N-methyl-D-aspartate (NMDA) receptor. Studies have shown that low-dose ketamine infusion results in a considerable reduction in obsessive-compulsive symptoms and a rapid resolution of suicidal ideation. This is a case report on the effect of intravenous ketamine infusion on a patient with resistant OCD and severe suicidal ideation. Intravenous (IV) ketamine was given once a week over consecutive three weeks with necessary precautions. Psychometric tools such as the Yale-Brown Obsessive Compulsive Scale (Y-BOCS), the Clinical Global Impressions Scale (CGI-S), the Beck Scale for Suicidal Ideations (BSSI), and Depression Anxiety and Stress Scale 21 (DASS-21) were applied before and after infusions. Obsessive-compulsive symptoms and suicidal severity started to decrease rapidly after the first infusion. However, after a transient improvement, these symptoms again began to increase after a stressful incident on the second day of the first infusion. All the symptoms measured by validated rating scales showed continued improvement after the following two infusions. The improvement was sustained until discharge (one week after the last infusion) and subsequent follow-up in the sixth and 12

Indexed as

bssicgi-scompulsionsdass-21depressionketamineobsessionsresistant ocdsuicidal ideation and attempty-bocs

Identifiers

PMID38596207
PMCPMC11002706
OpenAlexW4394614899

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.