Evidence map›Paper›PMID 38596316›Full record

ArticleComputational and structural biotechnology journal2024

Impact of an irreversible β-galactosylceramidase inhibitor on the lipid profile of zebrafish embryos.

Jessica Guerra, Mirella Belleri, Giulia Paiardi, Chiara Tobia, Davide Capoferri, Marzia Corli, Elisa Scalvini, Marco Ghirimoldi, Marcello Manfredi, Rebecca C Wade and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Computational and structural biotechnology journal, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. Molecular Dynamics Simulations of 4Computational and structural biotechnology journal · 2026
    Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 2 countries.

Jessica GuerraDepartment of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Mirella BelleriDepartment of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Giulia PaiardiDepartment of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Chiara TobiaDepartment of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Davide CapoferriDepartment of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Marzia CorliDepartment of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Elisa ScalviniDepartment of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Marco GhirimoldiDepartment of Translational Medicine, University of Piemonte Orientale, Novara, Italy.
Marcello ManfrediDepartment of Translational Medicine, University of Piemonte Orientale, Novara, Italy.
Rebecca C WadeMolecular and Cellular Modeling Group, Heidelberg Institute for Theoretical Studies, Germany.
Marco PrestaDepartment of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
Luca MignaniDepartment of Molecular and Translational Medicine, University of Brescia, Brescia, Italy.
University of Brescia · ITHeidelberg University · DEUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITConsorzio Interuniversitario per le Biotecnologie · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Krabbe disease is a sphingolipidosis characterized by the genetic deficiency of the acid hydrolase β-galactosylceramidase (GALC). Most of the studies concerning the biological role of GALC performed on Krabbe patients and

Indexed as

GalactosylceramidaseKrabbe diseaseLipidomicsMolecular modelingZebrafish

Identifiers

PMID38596316
PMCPMC11002810
OpenAlexW4393346096

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.