Evidence map›Paper›PMID 38598293›Full record

ArticleMolecular biology of the cell2024

WHAMM functions in kidney reabsorption and polymerizes actin to promote autophagosomal membrane closure and cargo sequestration.

Alyssa M Coulter, Valerie Cortés, Corey J Theodore, Rachel E Cianciolo, Ron Korstanje, Kenneth G Campellone

Open access · greenAbstract read
In one paragraph

Article in Molecular biology of the cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Alyssa M CoulterDepartment of Molecular & Cell Biology, Institute for Systems Genomics, University of Connecticut, Storrs, CT 06269.
Valerie CortésThe Jackson Laboratory, Bar Harbor, ME 04609.
Corey J TheodoreDepartment of Molecular & Cell Biology, Institute for Systems Genomics, University of Connecticut, Storrs, CT 06269.
Rachel E CiancioloNiche Diagnostics LLC, Columbus, OH 43201.
Ron KorstanjeThe Jackson Laboratory, Bar Harbor, ME 04609.
Kenneth G CampelloneDepartment of Molecular & Cell Biology, Institute for Systems Genomics, University of Connecticut, Storrs, CT 06269.ORCID 0000-0002-3178-9804
University of Connecticut · USJackson Laboratory · USMBio Diagnostics (United States) · US

Funding

Translational CoreP30AG038070 · NIA · JACKSON LABORATORY · PI John Matthew Mahoney · 2010 to 2026
$19.3M
Genetic Factors that Influence Arsenic ToxicityR01ES029916 · NIEHS · JACKSON LABORATORY · PI CHURCHILL, GARY A, KORSTANJE, RONNY · 2019 to 2023
$3.6M
Causal connections between axon guidance proteins and early progressive kidney function decline in diabetesR01DK131061 · NIDDK · JOSLIN DIABETES CENTER · PI KROLEWSKI, ANDRZEJ S · 2022 to 2025
$2.7M
Identification of Kidney Disease Modifier Genes in Mouse and Human Alport SyndromeR01DK131019 · NIDDK · JACKSON LABORATORY · PI KORSTANJE, RONNY · 2022 to 2025
$1.5M
Cytoskeletal control of membrane remodelingR01GM107441 · NIGMS · UNIVERSITY OF CONNECTICUT STORRS · PI CAMPELLONE, KENNETH G · 2014 to 2018
$1.4M
Cytoskeletal functions in cell aging and diseaseK02AG050774 · NIA · UNIVERSITY OF CONNECTICUT STORRS · PI CAMPELLONE, KENNETH G · 2016 to 2021
$838k
NIA NIH HHS K02 AG050774NIA NIH HHS P30 AG038070NIDDK NIH HHS R01 DK131019NIDDK NIH HHS R01 DK131061NIEHS NIH HHS R01 ES029916NIGMS NIH HHS R01 GM107441
6 · The paper itself

Abstract

The actin cytoskeleton is essential for many functions of eukaryotic cells, but the factors that nucleate actin assembly are not well understood at the organismal level or in the context of disease. To explore the function of the actin nucleation factor WHAMM in mice, we examined how

Indexed as

ActinsAutophagosomesAutophagyKidneyMice, KnockoutActin CytoskeletonActin-Related Protein 2-3 ComplexAnimalsFibroblastsHumansKidney Tubules, ProximalMaleMembrane ProteinsMiceMicrotubule-Associated ProteinsPolymerizationActin-Related Protein 2-3 ComplexActinsMembrane ProteinsMicrotubule-Associated ProteinsWHAMM protein, human

Identifiers

PMID38598293
PMCPMC11238085
OpenAlexW4394688589

What Socratic holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.