Evidence map›Paper›PMID 38600106›Full record

ArticleNature communications2024

Salmonella exploits membrane reservoirs for invasion of host cells.

Hongxian Zhu, Andrew M Sydor, Kirsten C Boddy, Etienne Coyaud, Estelle M N Laurent, Aaron Au, Joel M J Tan, Bing-Ru Yan, Jason Moffat, Aleixo M Muise and 4 more

Open access · goldAbstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
11.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. The Manipulation of Host Cells byInternational journal of molecular sciences · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. DietaryAntibiotics (Basel, Switzerland) · 2026
    Article
  8. Peptide PN5 fromACS omega · 2025
    Article
  9. Preassembly and independent trafficking of the exocyst complex inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Review
  12. Pathogen-induced rerouting of host membrane trafficking.Current opinion in cell biology · 2025
    Review
  13. Review
  14. The interplay betweenCell insight · 2025
    Review
  15. Article
  16. Review
  17. Article
  18. The exocyst in context.Biochemical Society transactions · 2024
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Hongxian ZhuCell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.
Andrew M SydorCell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.ORCID http://orcid.org/0000-0003-3585-0446
Kirsten C BoddyCell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.
Etienne CoyaudPrincess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.ORCID http://orcid.org/0000-0002-5893-4557
Estelle M N LaurentPrincess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
Aaron AuInstitute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.ORCID http://orcid.org/0000-0001-5717-048X
Joel M J TanCell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.ORCID http://orcid.org/0000-0002-6051-3786
Bing-Ru YanCell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.ORCID http://orcid.org/0000-0003-2138-7374
Jason MoffatDepartment of Molecular Genetics, University of Toronto, Toronto, ON, Canada.ORCID http://orcid.org/0000-0002-5663-8586
Aleixo M MuiseCell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.ORCID http://orcid.org/0000-0001-9624-3346
Christopher M YipInstitute of Biomedical Engineering, University of Toronto, Toronto, ON, Canada.ORCID http://orcid.org/0000-0003-4507-556X
Sergio GrinsteinCell Biology Program, Hospital for Sick Children, Toronto, ON, Canada.ORCID http://orcid.org/0000-0002-0795-4160
Brian RaughtPrincess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada.
John H BrumellCell Biology Program, Hospital for Sick Children, Toronto, ON, Canada. john.brumell@sickkids.ca.ORCID http://orcid.org/0000-0002-5802-7789
University of Toronto · CAHospital for Sick Children · CAUniversity Health Network · CA

Funding

COngenital Diarrhea and Enteropathy (PediCODE) Consortium and BioRepositoryRC2DK118640 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI James Richard Goldenring, Izumi Kaji · 2019 to 2026
$14.8M
Identifying Immune and Epithelial Network Signatures in Very Early Onset Inflammatory Bowel DiseaseRC2DK122532 · NIDDK · BOSTON CHILDREN'S HOSPITAL · PI KLEIN, CHRISTOPH, MUISE, ALEIXO M · 2020 to 2024
$9.1M
NIDDK NIH HHS RC2 DK118640NIDDK NIH HHS RC2 DK122532
6 · The paper itself

Abstract

Salmonella utilizes a type 3 secretion system to translocate virulence proteins (effectors) into host cells during infection

Indexed as

Salmonella InfectionsSalmonella typhimuriumBacterial ProteinsCell MembraneHeLa CellsHumansMembranesBacterial Proteins

Identifiers

PMID38600106
PMCPMC11006906
OpenAlexW4394674598

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.