Evidence map›Paper›PMID 38601953›Full record

Observational studyDevelopmental psychobiology2024

Examining the Biological Impacts of Parent-Child Relationship Dynamics on Preschool-Aged Children who have Experienced Adversity.

Jesse L Coe, Teresa Daniels, Lindsay Huffhines, Ronald Seifer, Carmen J Marsit, Hung-Teh Kao, Barbara Porton, Stephanie H Parade, Audrey R Tyrka

Open access · greenAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Developmental psychobiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
3.2field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Jesse L CoeDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Teresa DanielsDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Lindsay HuffhinesDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Ronald SeiferFrank Porter Graham Child Development Institute, The University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
Carmen J MarsitGangarosa Department of Environmental Health, Emory Rollins School of Public Health, Atlanta, GA, USA.
Hung-Teh KaoDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Barbara PortonDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Stephanie H ParadeDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Audrey R TyrkaDepartment of Psychiatry and Human Behavior, Warren Alpert Medical School of Brown University, Providence, RI, USA.
Brown University · USProvidence College · USEmory University · USUniversity of North Carolina at Chapel Hill · US

Funding

Project 3: Isolating food insecurity to understand childhood health outcomes and biological mechanisms of riskP20GM139767 · NIGMS · MIRIAM HOSPITAL · PI LAURA R STROUD · 2021 to 2026
$14.6M
RESEARCH TRAINING IN CHILD MENTAL HEALTHT32MH019927 · NIMH · RHODE ISLAND HOSPITAL (PROVIDENCE, RI) · PI Kristen G Benito, Anthony Spirito · 1994 to 2026
$7.8M
Risk Profiles and Mechanisms of Disease in Maltreated ChildrenR01HD086487 · NICHD · BUTLER HOSPITAL (PROVIDENCE, RI) · PI TYRKA, AUDREY · 2016 to 2020
$2.8M
Longitudinal examination of DNA methylation in maltreated childrenR01HD095837 · NICHD · EMMA PENDLETON BRADLEY HOSPITAL · PI PARADE, STEPHANIE HART · 2018 to 2022
$2.8M
Childhood Maltreatment:Biomarkers of Risk and ResilienceR01MH083704 · NIMH · BUTLER HOSPITAL (PROVIDENCE, RI) · PI TYRKA, AUDREY · 2010 to 2014
$2.6M
Research Training in Childhood Stress, Trauma, and ResilienceT32HD101392 · NICHD · MIRIAM HOSPITAL · PI PARADE, STEPHANIE HART, STROUD, LAURA R · 2020 to 2024
$1.7M
Enhancing early care and education through reflective supervision to promote adaptive emotion regulation in young childrenK23HD107243 · NICHD · EMMA PENDLETON BRADLEY HOSPITAL · PI Lindsay Huffhines · 2022 to 2026
$848k
NICHD NIH HHS K23 HD107243NICHD NIH HHS R01 HD086487NICHD NIH HHS R01 HD095837NICHD NIH HHS T32 HD101392NIGMS NIH HHS P20 GM139767NIMH NIH HHS R01 MH083704NIMH NIH HHS T32 MH019927
6 · The paper itself

Abstract

Parent-child relationship dynamics have been shown to predict socioemotional and behavioral outcomes for children, but little is known about how they may affect biological development. The aim of this study was to test if observational assessments of parent-child relationship dynamics (cohesion, enmeshment, and disengagement) were associated with three biological indices of early life adversity and downstream health risk: (1) methylation of the glucocorticoid receptor gene (

Indexed as

Child AbuseTelomere ShorteningChild, PreschoolDNA MethylationHumansParent-Child RelationsPovertyadversitymitochondriaNR3C1parent-child relationshippreschool-aged childrentelomere

Identifiers

PMID38601953
PMCPMC11003752
OpenAlexW4391319669

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.