Evidence map›Paper›PMID 38601975›Full record

ArticleSaudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society2024

Unveiling potent Schiff base derivatives with selective xanthine oxidase inhibition:

Fatna Bellahcene, Khedidja Benarous, Arif Mermer, Houssem Boulebd, Talia Serseg, Abderahmane Linani, Alaeddine Kaouka, Mohamed Yousfi, Asad Syed, Abdallah M Elgorban and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Saudi pharmaceutical journal : SPJ : the official publication of the Saudi Pharmaceutical Society, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
7.5field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 22 citations in OpenAlex.

  1. Article
  2. Article
  3. Molecular docking andJournal of Taibah University Medical Sciences · 2025
    Review
  4. Evaluation ofFood science & nutrition · 2025
    Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 6 institutions in 5 countries.

Fatna BellahceneLaboratory of Fundamental Sciences, Faculty of Sciences, University of Amar Telidji, Laghouat, Algeria.
Khedidja BenarousLaboratory of Fundamental Sciences, Faculty of Sciences, University of Amar Telidji, Laghouat, Algeria.
Arif MermerDepartment of Biotechnology, University of Health Sciences, İstanbul, Turkey.
Houssem BoulebdDepartment of Chemistry, Faculty of Exact Sciences, University of Constantine 1, Constantine, Algeria.
Talia SersegLaboratory of Fundamental Sciences, Faculty of Sciences, University of Amar Telidji, Laghouat, Algeria.
Abderahmane LinaniLaboratory of Fundamental Sciences, Faculty of Sciences, University of Amar Telidji, Laghouat, Algeria.
Alaeddine KaoukaLaboratoire des Sciences Appliquées et Didactiques, Ecole Normale Supérieure de Laghouat, Algeria.
Mohamed YousfiLaboratory of Fundamental Sciences, Faculty of Sciences, University of Amar Telidji, Laghouat, Algeria.
Asad SyedDepartment of Botany and Microbiology, College of Science, King Saud University, P.O. 2455, Riyadh 11451, Saudi Arabia.
Abdallah M ElgorbanDepartment of Botany and Microbiology, College of Science, King Saud University, P.O. 2455, Riyadh 11451, Saudi Arabia.
Yasuhiro OzekiGraduate School of NanoBio Sciences, Yokohama City University, 22-2 Seto, Kanazawa-ku, Yokohama 236-0027, Japan.
Sarkar M A KawsarLaboratory of Carbohydrate and Nucleoside Chemistry, Department of Chemistry, Faculty of Science, University of Chittagong, Chittagong 4331, Bangladesh.
University of Laghouat · DZKing Saud University · SAConstantine 1 University · DZSağlık Bilimleri Üniversitesi · TRUniversity of Chittagong · BDYokohama City University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This research describes the synthesis by an environmentally-friendly method, microwave irradiation, development and analysis of three novel and one previously identified Schiff base derivative as a potential inhibitor of bovine xanthine oxidase (BXO), a key enzyme implicated in the progression of gout. Meticulous experimentation revealed that these compounds (

Indexed as

GoutIn silico approachSchiff baseTriazoleXanthine oxidase inhibition

Identifiers

PMID38601975
PMCPMC11004395
OpenAlexW4393930513

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.