Evidence map›Paper›PMID 38603473›Full record

ReviewCirculation research2024

Environmental Exposome and Atrial Fibrillation: Emerging Evidence and Future Directions.

Sojin Youn Wass, Omar Hahad, Zain Asad, Shuo Li, Mina K Chung, Emelia J Benjamin, Khurram Nasir, Sanjay Rajagopalan, Sadeer G Al-Kindi

Open access · hybridAbstract readReview
In one paragraph

Review in Circulation research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 18 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Observational
  6. Review
  7. Article
  8. Article
  9. The impact of the Social Exposome in Cardiovascular Health and Disease.Journal of precision medicine (Amsterdam, Netherlands) · 2025
    Article
  10. Review
  11. Review
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 2 countries.

Sojin Youn WassHeart, Vascular and Thoracic Institute, Cleveland Clinic, OH (M.K.C., S.Y.W.).ORCID 0000-0001-9354-0011
Omar HahadDepartment of Cardiology, University Medical Center of the Johannes Gutenberg University Mainz, Germany (O.H.).ORCID 0000-0001-7823-7671
Zain AsadDivision of Cardiovascular Medicine, University of Oklahoma Medical Center, Oklahoma City (Z.A.).ORCID 0000-0003-3110-7049
Shuo LiBiomedical Engineering, Case Western Reserve University, Cleveland, OH (S.L.).ORCID 0000-0002-5184-3230
Mina K ChungHeart, Vascular and Thoracic Institute, Cleveland Clinic, OH (M.K.C., S.Y.W.).ORCID 0000-0002-7835-6045
Emelia J BenjaminSection of Cardiovascular Medicine, Department of Medicine, Boston Medical Center, Boston University Chobanian and Avedisian School of Medicine and Department of Epidemiology, Boston University School of Public Health, MA (E.J.B.).ORCID 0000-0003-4076-2336
Khurram NasirCardiovascular Prevention and Wellness, DeBakey Heart and Vascular Center, Houston Methodist, TX (K.N., S.G.A.-K.).ORCID 0000-0001-5376-2269
Sanjay RajagopalanHarrington Heart and Vascular Institute, University Hospitals, Cleveland, OH (S.R.).ORCID 0000-0001-6669-8163
Sadeer G Al-KindiCardiovascular Prevention and Wellness, DeBakey Heart and Vascular Center, Houston Methodist, TX (K.N., S.G.A.-K.).ORCID 0000-0002-1122-7695
Cleveland Clinic · USHouston Methodist · USBoston University · USCase Western Reserve University · USJohannes Gutenberg University Mainz · DEUniversity Hospitals of Cleveland · USUniversity of Oklahoma Medical Center · US

Funding

ACHIEVE P3 - CHDP50MD017351 · NIMHD · WAYNE STATE UNIVERSITY · PI LANFEAR, DAVID E · 2021 to 2025
$21.1M
IDENTIFICATION OF COMMON GENETIC VARIANTS FOR ATRIAL FIBRILLATION AND PR INTERVALR01HL092577 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI BENJAMIN, EMELIA J., ELLINOR, PATRICK THOMAS · 2009 to 2025
$20.6M
Project 3 Genes to Omics-Informed Drugs: Drug Repositioning and Testing to Prevent AF ProgressionsP01HL158502 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI Robert Alden Koeth · 2022 to 2026
$16.9M
Diversity Suppplement (CIRCADIAN) Circadian Disruption as Mediator of Cardiometabolic Risk in Air PollutionR35ES031702 · NIEHS · CASE WESTERN RESERVE UNIVERSITY · PI Sanjay Rajagopalan · 2021 to 2026
$5.9M
RADIOMIC APPROACHES TO IMPROVE TARGETING FOR ATRIAL FIBRILLATION CATHETER ABLATIONR01HL158071 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI BARNARD, JOHN, CHUNG, MINA KAY · 2021 to 2024
$2.9M
Diet-Environment Interactions in InflammationR01ES017290 · NIEHS · UNIVERSITY OF MARYLAND BALTIMORE · PI RAJAGOPALAN, SANJAY · 2010 to 2014
$1.8M
BLRD VA IK6 BX006185NHLBI NIH HHS P01 HL158502NHLBI NIH HHS R01 HL092577NHLBI NIH HHS R01 HL158071NIEHS NIH HHS R01 ES017290NIEHS NIH HHS R35 ES031702NIMHD NIH HHS P50 MD017351
6 · The paper itself

Abstract

There has been increased awareness of the linkage between environmental exposures and cardiovascular health and disease. Atrial fibrillation is the most common sustained cardiac arrhythmia, affecting millions of people worldwide and contributing to substantial morbidity and mortality. Although numerous studies have explored the role of genetic and lifestyle factors in the development and progression of atrial fibrillation, the potential impact of environmental determinants on this prevalent condition has received comparatively less attention. This review aims to provide a comprehensive overview of the current evidence on environmental determinants of atrial fibrillation, encompassing factors such as air pollution, temperature, humidity, and other meteorologic conditions, noise pollution, greenspace, and the social environment. We discuss the existing evidence from epidemiological and mechanistic studies, critically evaluating the strengths and limitations of these investigations and the potential underlying biological mechanisms through which environmental exposures may affect atrial fibrillation risk. Furthermore, we address the potential implications of these findings for public health and clinical practice and identify knowledge gaps and future research directions in this emerging field.

Indexed as

Air PollutionAtrial FibrillationCardiovascular SystemExposomeEnvironmental ExposureHumansair pollutionatrial fibrillationcardiovascular diseasesenvironmental exposureexposome

Identifiers

PMID38603473
PMCPMC11060886
OpenAlexW4394728248

What Socratic holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.