ArticleBMC biology2024
Chromosome-level genome assembly of Hippophae tibetana provides insights into high-altitude adaptation and flavonoid biosynthesis.
Article in BMC biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 15 citations in OpenAlex.
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- Phylogenomics provides comprehensive insights into the evolutionary relationships among cultivated buckwheat species.Genome biology · 2025Article
- Chromosome-level genome assembly of Hippophae salicifolia.Scientific data · 2025Article
- Characterization of the Mitochondrial Genome ofPlants (Basel, Switzerland) · 2025Article
- Assembly and Analysis of the Mitochondrial Genome ofPlants (Basel, Switzerland) · 2025Article
- The genome of Hippophae salicifolia provides new insights into the sexual differentiation of sea buckthorn.GigaScience · 2025Article
- Genetic diversity ofFrontiers in plant science · 2025Article
- Leaf stoichiometric characteristics and responses of sea-buckthorn (Frontiers in plant science · 2025Article
- Effects of Environmental Factors on the Diversity of Grasshopper Communities along Altitude Gradients in Xizang, China.Insects · 2024Article
- Development and validation of sex-linked molecular markers for rapid and accurate identification of male and female Hippophae tibetana plants.Scientific reports · 2024Article
- Complete mitochondrial genome ofFrontiers in plant science · 2024Article
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
Abstract
backgroundAs an endemic shrub of the Qinghai-Tibetan Plateau (QTP), the distribution of Hippophae tibetana Schlecht. ranges between 2800 and 5200 m above sea level. As the most basal branch of the Hippophae genus, H. tibetana has an extensive evolutionary history. The H. tibetana is a valuable tree for studying the ecological evolution of species under extreme conditions.
resultsHere, we generated a high-quality chromosome-level genome of H. tibetana. The total size of the assembly genome is 917 Mb. The phylogenomic analysis of 1064 single-copy genes showed a divergence between 3.4 and 12.8 Mya for H. tibetana. Multiple gene families associated with DNA repair and disease resistance were significantly expanded in H. tibetana. We also identified many genes related to DNA repair with signs of positive selection. These results showed expansion and positive selection likely play important roles in H. tibetana's adaptation to comprehensive extreme environments in the QTP. A comprehensive genomic and transcriptomic analysis identified 49 genes involved in the flavonoid biosynthesis pathway in H. tibetana. We generated transgenic sea buckthorn hairy root producing high levels of flavonoid.
conclusionsTaken together, this H. tibetana high-quality genome provides insights into the plant adaptation mechanisms of plant under extreme environments and lay foundation for the functional genomic research and molecular breeding of H. tibetana.
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