Evidence map›Paper›PMID 38610040›Full record

ArticleActa neuropathologica communications2024

Dysregulation of neuroprotective lipoxin pathway in astrocytes in response to cytokines and ocular hypertension​.

Shruthi Karnam, Shubham Maurya, Elainna Ng, Amodini Choudhary, Arzin Thobani, John G Flanagan, Karsten Gronert

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta neuropathologica communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Lipoxin BbioRxiv : the preprint server for biology · 2025
    Article
  9. Article
  10. Review
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Shruthi KarnamHerbert Wertheim School of Optometry and Vision Science, University of California Berkeley, Berkeley, CA, USA.
Shubham MauryaHerbert Wertheim School of Optometry and Vision Science, University of California Berkeley, Berkeley, CA, USA.
Elainna NgHerbert Wertheim School of Optometry and Vision Science, University of California Berkeley, Berkeley, CA, USA.
Amodini ChoudharyHerbert Wertheim School of Optometry and Vision Science, University of California Berkeley, Berkeley, CA, USA.
Arzin ThobaniHerbert Wertheim School of Optometry and Vision Science, University of California Berkeley, Berkeley, CA, USA.
John G FlanaganHerbert Wertheim School of Optometry and Vision Science, University of California Berkeley, Berkeley, CA, USA. jgflanagan@berkeley.edu.
Karsten GronertHerbert Wertheim School of Optometry and Vision Science, University of California Berkeley, Berkeley, CA, USA. kgronert@berkeley.edu.
University of California, Berkeley · US

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
UC Berkeley Vision Science COREP30EY003176 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI KARSTEN GRONERT · 1985 to 2026
$16.4M
Homeostatic Role and Therapeutic Potential of the Neuroprotective Retinal Lipoxin CircuitR01EY030218 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI FLANAGAN, JOHN G, GRONERT, KARSTEN · 2020 to 2024
$2.4M
NEI NIH HHS P30 EY003176NEI NIH HHS R01 EY030218NEI NIH HHS R01EY030218NIH HHS P51 OD011092
6 · The paper itself

Abstract

Glaucoma leads to vision loss due to retinal ganglion cell death. Astrocyte reactivity contributes to neurodegeneration. Our recent study found that lipoxin B

Indexed as

GlaucomaLipoxinsOcular HypertensionAnimalsAstrocytesCytokinesDisease Models, AnimalHumansMicePrimatesRetinaCytokinesLipoxinsAstrocyte reactivityGlaucomaLipoxin B4LipoxygenaseNeurodegenerationOptic nerveRetina

Identifiers

PMID38610040
PMCPMC11010376
OpenAlexW4394764710

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.