Evidence map›Paper›PMID 38610736›Full record

ReviewJournal of clinical medicine2024

Beyond the Cold: Activating Brown Adipose Tissue as an Approach to Combat Obesity.

Cristina Elena Negroiu, Iulia Tudorașcu, Cristina Maria Bezna, Sanziana Godeanu, Marina Diaconu, Raluca Danoiu, Suzana Danoiu

Open access · goldAbstract readReview
In one paragraph

Review in Journal of clinical medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Perirenal Fat in Disease Progression: From Inflammatory Mediator to Therapeutic Target.International journal of urology : official journal of the Japanese Urological Association · 2025
    Review
  8. Review
  9. Article
  10. Effect of Diet on HDL in Obesity.Molecules (Basel, Switzerland) · 2024
    Review
  11. Article
  12. Physical exercise and irisin: managing obesity and related comorbidities.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Cristina Elena NegroiuDepartment of Pathophysiology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Iulia TudorașcuDepartment of Pathophysiology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Cristina Maria BeznaDepartment of Pathophysiology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Sanziana GodeanuDoctoral School, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.
Marina DiaconuDepartment of Radiology, County Clinical Emergency Hospital of Craiova, 200642 Craiova, Romania.
Raluca DanoiuDepartment of Social Sciences and Humanities, University of Craiova, 200585 Craiova, Romania.
Suzana DanoiuDepartment of Pathophysiology, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania.ORCID 0000-0003-0785-0123
University of Medicine and Pharmacy of Craiova · ROUniversity of Craiova · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

With a dramatic increase in the number of obese and overweight people, there is a great need for new anti-obesity therapies. With the discovery of the functionality of brown adipose tissue in adults and the observation of beige fat cells among white fat cells, scientists are looking for substances and methods to increase the activity of these cells. We aimed to describe how scientists have concluded that brown adipose tissue is also present and active in adults, to describe where in the human body these deposits of brown adipose tissue are, to summarize the origin of both brown fat cells and beige fat cells, and, last but not least, to list some of the substances and methods classified as BAT promotion agents with their benefits and side effects. We summarized these findings based on the original literature and reviews in the field, emphasizing the discovery, function, and origins of brown adipose tissue, BAT promotion agents, and batokines. Only studies written in English and with a satisfying rating were identified from electronic searches of PubMed.

Indexed as

beige fat cellbrown adipose tissuebrowning agentFGF21obesity

Identifiers

PMID38610736
PMCPMC11012454
OpenAlexW4393279507

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.