Evidence map›Paper›PMID 38612434›Full record

ArticleInternational journal of molecular sciences2024

DEAD Box Helicase 24 Is Increased in the Brain in Alzheimer's Disease and

Michael Axenhus, Tosca Doeswijk, Per Nilsson, Anna Matton, Bengt Winblad, Lars Tjernberg, Sophia Schedin-Weiss

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Michael AxenhusDepartment of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, 171 64 Solna, Sweden.
Tosca DoeswijkDepartment of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, 171 64 Solna, Sweden.
Per NilssonDepartment of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, 171 64 Solna, Sweden.ORCID 0000-0001-6450-0870
Anna MattonDepartment of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, 171 64 Solna, Sweden.ORCID 0000-0002-7819-0495
Bengt WinbladDepartment of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, 171 64 Solna, Sweden.
Lars TjernbergDepartment of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, 171 64 Solna, Sweden.
Sophia Schedin-WeissDepartment of Neurobiology, Care Sciences and Society, Division of Neurogeriatrics, Karolinska Institutet, 171 64 Solna, Sweden.
Karolinska Institutet · SEKarolinska University Hospital · SE

Funding

Margaretha af Ugglas' foundation N/Athe Foundation for Old Handmades (2021-01205 and 2022-01368).the Swedish Brain Foundation (FO2021-0416)the Swedish Research Council ( (2017-91874)
6 · The paper itself

Abstract

At the time of diagnosis, Alzheimer's disease (AD) patients already suffer from significant neuronal loss. The identification of proteins that influence disease progression before the onset of symptoms is thus an essential part of the development of new effective drugs and biomarkers. Here, we used an unbiased

Indexed as

Alzheimer DiseaseAmyloidogenic ProteinsAnimalsBrainCell NucleolusDEAD-box RNA HelicasesHumansMiceAmyloidogenic ProteinsDDX24 protein, humanDdx24 protein, mouseDEAD-box RNA HelicasesAlzheimer’s diseaseDDX24hippocampusimmunohistochemistrypost-mortem brain

Identifiers

PMID38612434
PMCPMC11011903
OpenAlexW4393150113

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.