Evidence map›Paper›PMID 38612533›Full record

ArticleInternational journal of molecular sciences2024

Stool Glycoproteomics Signatures of Pre-Cancerous Lesions and Colorectal Cancer.

Janine Soares, Mariana Eiras, Dylan Ferreira, Daniela A R Santos, Marta Relvas-Santos, Beatriz Santos, Martina Gonçalves, Eduardo Ferreira, Renata Vieira, Luís Pedro Afonso and 4 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Janine SoaresExperimental Pathology and Therapeutics Group, Research Center of IPO Porto (CI-IPOP), RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto), Porto Comprehensive Cancer Center Raquel Seruca (Porto.CCC Raquel Seruca), 4200-072 Porto, Portugal.ORCID 0000-0002-1586-7120
Mariana EirasExperimental Pathology and Therapeutics Group, Research Center of IPO Porto (CI-IPOP), RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto), Porto Comprehensive Cancer Center Raquel Seruca (Porto.CCC Raquel Seruca), 4200-072 Porto, Portugal.ORCID 0009-0006-7483-4771
Dylan FerreiraExperimental Pathology and Therapeutics Group, Research Center of IPO Porto (CI-IPOP), RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto), Porto Comprehensive Cancer Center Raquel Seruca (Porto.CCC Raquel Seruca), 4200-072 Porto, Portugal.ORCID 0000-0001-9224-0121
Daniela A R SantosExperimental Pathology and Therapeutics Group, Research Center of IPO Porto (CI-IPOP), RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto), Porto Comprehensive Cancer Center Raquel Seruca (Porto.CCC Raquel Seruca), 4200-072 Porto, Portugal.ORCID 0000-0003-1081-5142
Marta Relvas-SantosExperimental Pathology and Therapeutics Group, Research Center of IPO Porto (CI-IPOP), RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto), Porto Comprehensive Cancer Center Raquel Seruca (Porto.CCC Raquel Seruca), 4200-072 Porto, Portugal.ORCID 0000-0001-5764-5414
Beatriz SantosExperimental Pathology and Therapeutics Group, Research Center of IPO Porto (CI-IPOP), RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto), Porto Comprehensive Cancer Center Raquel Seruca (Porto.CCC Raquel Seruca), 4200-072 Porto, Portugal.
Martina GonçalvesExperimental Pathology and Therapeutics Group, Research Center of IPO Porto (CI-IPOP), RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto), Porto Comprehensive Cancer Center Raquel Seruca (Porto.CCC Raquel Seruca), 4200-072 Porto, Portugal.
Eduardo FerreiraExperimental Pathology and Therapeutics Group, Research Center of IPO Porto (CI-IPOP), RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto), Porto Comprehensive Cancer Center Raquel Seruca (Porto.CCC Raquel Seruca), 4200-072 Porto, Portugal.
Renata VieiraDepartment of Pathology, Portuguese Oncology Institute of Porto, 4200-072 Porto, Portugal.
Luís Pedro AfonsoExperimental Pathology and Therapeutics Group, Research Center of IPO Porto (CI-IPOP), RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto), Porto Comprehensive Cancer Center Raquel Seruca (Porto.CCC Raquel Seruca), 4200-072 Porto, Portugal.
Lúcio Lara SantosExperimental Pathology and Therapeutics Group, Research Center of IPO Porto (CI-IPOP), RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto), Porto Comprehensive Cancer Center Raquel Seruca (Porto.CCC Raquel Seruca), 4200-072 Porto, Portugal.
Mário Dinis-RibeiroFaculty of Medicine (FMUP), University of Porto, 4200-072 Porto, Portugal.
Luís LimaExperimental Pathology and Therapeutics Group, Research Center of IPO Porto (CI-IPOP), RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto), Porto Comprehensive Cancer Center Raquel Seruca (Porto.CCC Raquel Seruca), 4200-072 Porto, Portugal.
José Alexandre FerreiraExperimental Pathology and Therapeutics Group, Research Center of IPO Porto (CI-IPOP), RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto), Porto Comprehensive Cancer Center Raquel Seruca (Porto.CCC Raquel Seruca), 4200-072 Porto, Portugal.ORCID 0000-0002-0097-6148
Instituto Português de Oncologia Francisco Gentil · PTUniversidade do Porto · PTFernando Pessoa University · PT

Funding

COMPUTER AIDED ANALYSIS OF ELECTROCARDIOGRAPHYZ01CT000002 · CIT · COMPUTER RESEARCH AND TECHNOLOGY · PI BAILEY, JAMES J. · 1985 to 2003
–
Fundação para a Ciência e Tecnologia 2020.09384.BDFundação para a Ciência e Tecnologia 2022.08311.CEECINDFundação para a Ciência e Tecnologia CEECIND/03186/2017Fundação para a Ciência e Tecnologia CI-IPOP-776_6_BDFundação para a Ciência e Tecnologia COVID/BD/153011/2023Fundação para a Ciência e Tecnologia http://doi.org/10.54499/2022.09051.PTDCFundação para a Ciência e Tecnologia https://doi.org/10.54499/PTDC/MED-OUT/2512/2021Fundação para a Ciência e Tecnologia SFRH/BD/142479/2018Fundação para a Ciência e Tecnologia SFRH/BD/146500/2019Fundação para a Ciência e Tecnologia UIDP/00776/2020Intramural NIH HHS Z01 CT000002
6 · The paper itself

Abstract

Colorectal cancer (CRC) screening relies primarily on stool analysis to identify occult blood. However, its sensitivity for detecting precancerous lesions is limited, requiring the development of new tools to improve CRC screening. Carcinogenesis involves significant alterations in mucosal epithelium glycocalyx that decisively contribute to disease progression. Building on this knowledge, we examined patient series comprehending premalignant lesions, colorectal tumors, and healthy controls for the T-antigen-a short-chain

Indexed as

Colorectal NeoplasmsPrecancerous ConditionsAntigens, Viral, TumorCarcinogenesisHumansHyperplasiaAntigens, Viral, Tumorcancer glycosylationcolorectal cancerglycoproteomicspre-cancerous lesionsstool glycoproteins

Identifiers

PMID38612533
PMCPMC11012158
OpenAlexW4393235056

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.