Evidence map›Paper›PMID 38612988›Full record

ArticleNutrients2024

Preventative Effects of Milk Fat Globule Membrane Ingredients on DSS-Induced Mucosal Injury in Intestinal Epithelial Cells.

Erica Kosmerl, Celeste Miller, Rafael Jiménez-Flores

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nutrients, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.9field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Erica KosmerlDepartment of Food Science and Technology, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-0751-4990
Celeste MillerDepartment of Food Science and Technology, The Ohio State University, Columbus, OH 43210, USA.ORCID 0009-0003-8784-1290
Rafael Jiménez-FloresDepartment of Food Science and Technology, The Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0003-4905-5021
The Ohio State University · US

Funding

JT Parker Endowment 0001
6 · The paper itself

Abstract

The goblet cells of the gastrointestinal tract (GIT) produce glycoproteins called mucins that form a protective barrier from digestive contents and external stimuli. Recent evidence suggests that the milk fat globule membrane (MFGM) and its milk phospholipid component (MPL) can benefit the GIT through improving barrier function. Our objective was to compare the effects of two digested MFGM ingredients with or without dextran sodium sulfate (DSS)-induced barrier stress on mucin proteins. Co-cultured Caco-2/HT29-MTX intestinal cells were treated with in vitro digests of 2%, 5%, and 10% (

Indexed as

DextransGlycolipidsGlycoproteinsLipid DropletsAlcian BlueCaco-2 CellsEpithelial CellsFluorescein-5-isothiocyanateHumansMucinsAlcian BlueDextransFluorescein-5-isothiocyanatefluorescein isothiocyanate dextranGlycolipidsGlycoproteinsmilk fat globuleMucinscell cultureHT29-MTXin vitro digestionmilk fat globule membranemucinphospholipidsscanning electron microscopy

Identifiers

PMID38612988
PMCPMC11013169
OpenAlexW4393201194

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.