ArticleHealth and quality of life outcomes2024
Longitudinal course and predictors of health-related quality of life, mental health, and fatigue, in non-hospitalized individuals with or without post COVID-19 syndrome.
Article in Health and quality of life outcomes, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Systematic Review of Dyspnea and Chronic Fatigue in Patients With Long COVID: Clinical Characteristics and Associated Laboratory Parameters.Pulmonary medicine · 2026Pooled it
- Latent profile analysis of the symptoms for posttraumatic stress disorder and psychological resilience in Chinese adolescents experiencing post Covid-19: a quantetative study.BMC psychology · 2026Article
- Observational
- Prospective associations between Long COVID and mental health: evidence from a population-based study with a nearly three-year follow-up.BMC public health · 2026Article
- Effects of the COVID-19 pandemic on working conditions and mental health among employees in health and social services.Frontiers in public health · 2026Article
- Impact of COVID-19 on Health-Related Quality of Life and Mental Health Among Employees in Health and Social Services-A Longitudinal Study.Infectious disease reports · 2025Article
- Long-COVID symptom burden and the experience of adversity: the importance of response-shift effects over 3 years of the pandemic.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2025Article
- Pre-COVID health-related quality of life predicts symptoms and outcomes for patients with long COVID.Frontiers in public health · 2025Article
- The health-related quality of life among survivors with post-COVID conditions in the United States.PloS one · 2025Article
- COVID-19 and the impact of physical activity on persistent symptoms.Frontiers in sports and active living · 2025Article
- The faces of Long-COVID: interplay of symptom burden with socioeconomic, behavioral and healthcare factors.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2024Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundLong-term information on health-related quality of life (HRQOL) and mental health of non-hospitalized individuals with "post COVID-19 syndrome" (PCS) is scarce. Thus, the objectives of the present study were to compare HRQOL and mental health of individuals with and without PCS in a German sample of non-hospitalized persons after SARS-CoV-2 infection, to characterize the long-term course up to 2 years and to identify predictors for post COVID-19 impairments.
methodsIndividuals with past SARS-CoV-2 infection were examined at the University Hospital of Augsburg from November 2020 to May 2021 and completed a postal questionnaire between June and November 2022. Participants who self-reported the presence of fatigue, dyspnea on exertion, memory problems or concentration problems were classified as having PCS. HRQOL was assessed using the Veterans RAND 12-Item Health Survey, mental health was measured by the Patient Health Questionnaire and the Fatigue Asessment Scale was used to assess fatigue severity. Multivariable linear regression models with inverse probability weighting were used to determine the association between PCS and health outcomes.
resultsFrom the 304 participants (58.2% women, median age 52 years), 210 (69.1%) were classified as having PCS in median 26 months after SARS-CoV-2 infection. Persons with PCS showed significantly more often depressive and anxiety disorders. PCS was independently and significantly associated with higher levels of depression, post-traumatic stress and fatigue, as well as poorer physical and mental HRQOL in median 9 months as well as 26 months after SARS-CoV-2 infection. A large number of acute symptoms and a prior diagnosis of depression were independently associated with poor mental health and HRQOL. While post-traumatic stress and mental HRQOL improved from 9 months to 26 months post infection onset, depressiveness, fatigue and physical HRQOL remained stable in both, persons with and without PCS.
conclusionsPCS in non-hospitalized persons after SARS-CoV-2 infection is often associated with long-term impairments of mental health and HRQOL outcomes.
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