Evidence map›Paper›PMID 38617049›Full record

ArticleResearch and practice in thrombosis and haemostasis2024

Perioperative management of venous recanalization in a patient with inherited antithrombin deficiency: case report.

Julie Benzakine, Carla Rial, Nassim Mohamedi, Emmanuel Messas, Laetitia Mauge, Marc Sapoval, Nicolas Gendron, Lina Khider

Open access · goldAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Research and practice in thrombosis and haemostasis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Julie BenzakineInnovative Therapies in Haemostasis, INSERM, University Paris Cité, Paris, France.
Carla RialInnovative Therapies in Haemostasis, INSERM, University Paris Cité, Paris, France.
Nassim MohamediVascular Medicine Department, Assistance Publique Hôpitaux de Paris, Centre-University Paris Cité, Paris, France.
Emmanuel MessasVascular Medicine Department, Assistance Publique Hôpitaux de Paris, Centre-University Paris Cité, Paris, France.
Laetitia MaugeHematology Department, Assistance Publique Hôpitaux de Paris, Centre-Université de Paris, Paris, France.
Marc SapovalParis Cardiovascular Research Centre, INSERM, Hematology Department, Assistance Publique Hôpitaux de Paris, Centre-Université de Paris (APHP-CUP), Paris, France.
Nicolas GendronInnovative Therapies in Haemostasis, INSERM, University Paris Cité, Paris, France.
Lina KhiderInnovative Therapies in Haemostasis, INSERM, University Paris Cité, Paris, France.
Assistance Publique – Hôpitaux de Paris · FRInserm · FRSorbonne Paris Cité · FRUniversité Paris Cité · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Inherited antithrombin (AT) deficiency (ATD) is a severe thrombophilia causing venous thromboembolism, which can be complicated by postthrombotic syndrome (PTS). Venous recanalization, used to treat PTS, often requires a temporary withdrawal of anticoagulant therapy. In ATD patients, there is a risk of insufficient perioperative anticoagulation due to altered heparin response. Key Clinical Question: There is no consensus on how to manage perioperative anticoagulation in ATD patients. Clinical Approach: Warfarin-unfractionated heparin transition could be a more reliable strategy than low-molecular-weight heparin transition because unfractionated heparin anti-Xa activity not only reflects heparin-bound AT but also AT's activity, which correlates strongly with therapeutic anticoagulation. Biological monitoring could thus decrease the number of plasma-derived AT supplementation. Conclusion: This study describes a successful perioperative management of anticoagulation for venous recanalization that could be suggested to type 1 ATD patients with PTS.

Indexed as

antithrombin deficiencyperioperative anticoagulation managementpostthrombotic syndromeunfractionated heparinvenous recanalizationvenous thromboembolism

Identifiers

PMID38617049
PMCPMC11015152
OpenAlexW4392859305

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.