Evidence map›Paper›PMID 38618170›Full record

ReviewBMJ medicine2024

Neonatal hypoglycaemia.

Jane E Harding, Jane M Alsweiler, Taygen E Edwards, Chris Jd McKinlay

Open access · goldAbstract readReview
In one paragraph

Review in BMJ medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 2 pooled it
9.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Improving timing of early neonatal hypoglycemia screening in the well-baby nursery.Journal of perinatology : official journal of the California Perinatal Association · 2026
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. The influence of interleukin-27 on metabolic fitness in a murine neonatal model of bacterial sepsis.American journal of physiology. Endocrinology and metabolism · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jane E HardingLiggins Institute, University of Auckland, Auckland, New Zealand.ORCID 0000-0003-2697-1422
Jane M AlsweilerDepartment of Paediatrics: Child and Youth Health, University of Auckland, Auckland, New Zealand.
Taygen E EdwardsLiggins Institute, University of Auckland, Auckland, New Zealand.
Chris Jd McKinlayDepartment of Paediatrics: Child and Youth Health, University of Auckland, Auckland, New Zealand.
University of Auckland · NZ

Funding

"Two year outcomes after dextrose gel prophylaxis for neonatal hypoglycaemia"R01HD091075 · NICHD · UNIVERSITY OF AUCKLAND · PI HARDING, JANE · 2018 to 2022
$2.0M
NICHD NIH HHS R01 HD091075
6 · The paper itself

Abstract

Low blood concentrations of glucose (hypoglycaemia) soon after birth are common because of the delayed metabolic transition from maternal to endogenous neonatal sources of glucose. Because glucose is the main energy source for the brain, severe hypoglycaemia can cause neuroglycopenia (inadequate supply of glucose to the brain) and, if severe, permanent brain injury. Routine screening of infants at risk and treatment when hypoglycaemia is detected are therefore widely recommended. Robust evidence to support most aspects of management is lacking, however, including the appropriate threshold for diagnosis and optimal monitoring. Treatment is usually initially more feeding, with buccal dextrose gel, followed by intravenous dextrose. In infants at risk, developmental outcomes after mild hypoglycaemia seem to be worse than in those who do not develop hypoglycaemia, but the reasons for these observations are uncertain. Here, the current understanding of the pathophysiology of neonatal hypoglycaemia and recent evidence regarding its diagnosis, management, and outcomes are reviewed. Recommendations are made for further research priorities.

Indexed as

EndocrinologyNeonatologyNeuropathologyPerinatology

Identifiers

PMID38618170
PMCPMC11015200
OpenAlexW4394688197

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.