Evidence map›Paper›PMID 38618576›Full record

ArticleGeburtshilfe und Frauenheilkunde2024

The NFκB Signaling Pathway Is Involved in the Pathophysiological Process of Preeclampsia.

Yaxi Li, Qinying Zhu, Ruifen He, Junhong Du, Xue Qin, Yi Li, Xiaolei Liang, Jing Wang

Open access · hybridAbstract read
In one paragraph

Article in Geburtshilfe und Frauenheilkunde, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Yaxi LiThe First Clinical Medical College of Lanzhou University, Lanzhou, China.
Qinying ZhuThe First Clinical Medical College of Lanzhou University, Lanzhou, China.
Ruifen HeThe First Clinical Medical College of Lanzhou University, Lanzhou, China.
Junhong DuThe First Clinical Medical College of Lanzhou University, Lanzhou, China.
Xue QinThe First Clinical Medical College of Lanzhou University, Lanzhou, China.
Yi LiThe First Clinical Medical College of Lanzhou University, Lanzhou, China.
Xiaolei LiangDepartment of Obstetrics and Gynecology, Key Laboratory for Gynecologic Oncology Gansu Province, The First Hospital of Lanzhou University, Lanzhou, China.
Jing WangDepartment of Obstetrics and Gynecology, The First Hospital of Lanzhou University, Lanzhou, China.ORCID 0000-0001-5978-4709
First Hospital of Lanzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The high prevalence of preeclampsia (PE) is a major cause of maternal and fetal mortality and affects the long-term prognosis of both mother and baby. Termination of pregnancy is currently the only effective treatment for PE, so there is an urgent need for research into its pathogenesis and the development of new therapeutic approaches. The NFκB family of transcription factors has an essential role in inflammation and innate immunity. In this review, we summarize the role of NFκB in normal and preeclampsia pregnancies, the role of NFκB in existing treatment strategies, and potential NFκB treatment strategies.

Indexed as

inflammationNFκBpreeclampsia (PE)pregnancytreatment

Identifiers

PMID38618576
PMCPMC11006561
OpenAlexW4394694837

What Socratic holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.