Evidence map›Paper›PMID 38624244›Full record

ReviewPhysiology (Bethesda, Md.)2024

Unraveling the Enigma of Organismal Death: Insights, Implications, and Unexplored Frontiers.

Peter A Noble, Alexander Pozhitkov, Kanhaiya Singh, Erik Woods, Chunyu Liu, Michael Levin, Gulnaz Javan, Jun Wan, Ahmed Safwat Abouhashem, Shomita S Mathew-Steiner and 1 more

Abstract readReview
In one paragraph

Review in Physiology (Bethesda, Md.), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Peter A NobleDepartment of Microbiology, University of Alabama Birmingham, Birmingham, Alabama, United States.ORCID 0000-0002-6013-2588
Alexander PozhitkovDivision of Research Informatics, Beckman Research Institute, City of Hope, Duarte, California, United States.
Kanhaiya SinghDepartment of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.
Erik WoodsOssium Health, Indianapolis, Indiana, United States.
Chunyu LiuInstitute for Human Performance, Upstate Medical University, Syracuse, New York, United States.
Michael LevinDepartment of Biology, Tufts University, Medford, Massachusetts, United States.
Gulnaz JavanDepartment of Physical and Forensic Sciences, Alabama State University, Montgomery, Alabama, United States.ORCID 0000-0002-0957-0603
Jun WanDepartment of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.
Ahmed Safwat AbouhashemDepartment of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, Indiana, United States.
Shomita S Mathew-SteinerDepartment of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.
Chandan K SenDepartment of Surgery, McGowan Institute for Regenerative Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.

Funding

Investigating microbiota of the gut-brain axis and the impact of cocaineR16GM149358 · NIGMS · ALABAMA STATE UNIVERSITY · PI JAVAN, GULNAZ · 2023 to 2025
$370k
Bill and Ann Templeton Foundation (The Bill & Ann Templeton Foundation, Inc.) 61742HHS | National Institutes of Health (NIH) R16GM149358National Science Foundation (NSF) EES 2011764NIGMS NIH HHS R16 GM149358
6 · The paper itself

Abstract

Significant knowledge gaps exist regarding the responses of cells, tissues, and organs to organismal death. Examining the survival mechanisms influenced by metabolism and environment, this research has the potential to transform regenerative medicine, redefine legal death, and provide insights into life's physiological limits, paralleling inquiries in embryogenesis.

Indexed as

DeathAnimalsHumansorganismal deathphysiological limitssurvival mechanismstransformationtransitions

Identifiers

PMID38624244
PMCPMC11460531

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.