ReviewDiabetologia2024
Prevention and treatment of ischaemic and haemorrhagic stroke in people with diabetes mellitus: a focus on glucose control and comorbidities.
Review in Diabetologia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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The trial behind it
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Who cites it
21 citing papers in PubMed, 22 citations in OpenAlex.
- Blood glucose trajectory phenotypes are associated with in-hospital mortality in a multicenter ICU stroke cohort.Scientific reports · 2026Article
- Bringing a mobile multidisciplinary clinic to the bedside in a regional dialysis center for patients with diabetes: Responding to our patients' needs.Irish journal of medical science · 2026Article
- Semaglutide targets the Isg15-FUNDC1 axis: suppressing IFN-β overactivation and attenuating blood-brain barrier injury in diabetic intracerebral hemorrhage.Journal of neuroinflammation · 2026Article
- National trends and comparative outcomes of insulin versus non-insulin therapy in acute ischemic stroke patients treated with mechanical thrombectomy: a retrospective cohort study using the national inpatient sample.Neurosurgical review · 2026Article
- Diabetes Mellitus and Stroke: Pathophysiological Connections and Therapeutic Potential of GLP-1 and GLP-1/GIP Receptor Agonists.Pharmaceutics · 2026Review
- An interpretable machine learning model for predicting stroke in patients with hypertension: insights from the SPRINT.Scientific reports · 2026Article
- Association of the triglyceride glucose-body roundness index with stroke risk in middle-aged and elderly Chinese adults without diabetes: a prospective cohort study.Cardiovascular diagnosis and therapy · 2026Article
- Assessment of Socio-Demographic and Clinical Characteristics of Stroke Patients of a Tertiary Hospital in Bangladesh: A Cross-Sectional Study.Health science reports · 2026Article
- Factors associated with stroke among patients with hypertension in Eastern Ethiopia: a case-control study.BMC neurology · 2026Article
- Association of C-reactive protein/high-density lipoprotein cholesterol ratio with stroke in Chinese adults across different glycemic status.Lipids in health and disease · 2026Article
- Trends in diabetes and stroke-related mortality in the United States, 1999-2024: a population-based analysis.Annals of medicine and surgery (2012) · 2026Review
- Type 2 Diabetes-Related Complications Among Commercial Pilots: Aeromedical Considerations from a Retrospective Cohort.Journal of multidisciplinary healthcare · 2026Article
- Heart Rate Variability Dynamics as Predictors of Functional Recovery and Mortality After Acute Ischemic Stroke.Biomedicines · 2025Article
- Systolic Blood Pressure Variability in Acute Ischemic Stroke: A Predictor of Infarct Growth and Hemorrhagic Transformation.Biomedicines · 2025Article
- Stress Hyperglycemia as a Prognostic Indicator of the Clinical Outcomes in Patients with Stroke: A Comprehensive Literature Review.Biomedicines · 2025Review
- Exploration of the shared gene signatures and molecular mechanisms between cardioembolic stroke and ischemic stroke.Frontiers in neurology · 2025Article
- Secondary stroke prevention beyond antiplatelets: The role of colchicine and GLP-1RA - an ounce of prevention is worth a pound of cure.Therapeutic advances in neurological disorders · 2025Review
- Development and validation of a machine learning-based model for perioperative stroke prediction in noncardiac, nonvascular, and nonneurosurgical patients.Frontiers in physiology · 2025Article
- Observational
- Anesthetic Management of Acute Ischemic Stroke Undergoing Mechanical Thrombectomy: An Overview.Diagnostics (Basel, Switzerland) · 2024Review
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Diabetes mellitus is a significant risk factor for both ischaemic and haemorrhagic stroke, affecting up to a third of individuals with cerebrovascular diseases. Beyond being a risk factor for stroke, diabetes and hyperglycaemia have a negative impact on outcomes after ischaemic and haemorrhagic stroke. Hyperglycaemia during the acute ischaemic stroke phase is associated with a higher risk of haemorrhagic transformation and poor functional outcome, with evidence in favour of early intervention to limit and manage severe hyperglycaemia. Similarly, intensive glucose control nested in a broader bundle of care, including blood pressure, coagulation and temperature control, can provide substantial benefit for clinical outcomes after haemorrhagic stroke. As micro- and macrovascular complications are frequent in people with diabetes, cardiovascular prevention strategies also need to consider tailored treatment. In this regard, the broader availability of sodium-glucose cotransporter 2 inhibitors and glucagon-like peptide 1 receptor agonists can allow tailored treatments, particularly for those with heart failure and chronic kidney disease as comorbidities. Here, we review the main concepts of hyperacute stroke management and CVD prevention among people with diabetes, capitalising on results from large studies and RCTs to inform clinicians on preferred treatments.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.