Evidence map›Paper›PMID 38627031›Full record

GuidelineGut2024

British Society of Gastroenterology guidelines for the management of hepatocellular carcinoma in adults.

Abid Suddle, Helen Reeves, Richard Hubner, Aileen Marshall, Ian Rowe, Dina Tiniakos, Stefan Hubscher, Mark Callaway, Dinesh Sharma, Teik Choon See and 4 more

Abstract readPractice Guideline
In one paragraph

Guideline in Gut, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Progression to Decompensation of Severe Fibrosis Compared to Cirrhosis in MASLD: A Systematic Review and Meta-Analysis.Liver international : official journal of the International Association for the Study of the Liver · 2026
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Improving surgical treatments for hepatocellular carcinoma.Nature reviews. Gastroenterology & hepatology · 2026
    Review
  11. Article
  12. Article
  13. Antigen-specific CD8British journal of cancer · 2026
    Article
  14. Review
  15. Article
  16. Review
  17. The UK National Appeals Panel Safely Extends Access to Liver Transplantation for Candidates Beyond Standard Listing Criteria.Transplant international : official journal of the European Society for Organ Transplantation · 2026
    Article
  18. Article
  19. Review
  20. Myeloid cells in chronic liver inflammation.Cellular & molecular immunology · 2025
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Abid SuddleKing's College Hospital NHS Foundation Trust, London, UK abid.suddle@nhs.net.ORCID 0000-0002-2415-5352
Helen ReevesNewcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.
Richard HubnerDepartment of Oncology, The Christie NHS Foundation Trust, Manchester, UK.
Aileen MarshallRoyal Free London NHS Foundation Trust, London, UK.
Ian RoweUniversity of Leeds, Leeds, UK.
Dina TiniakosInstitute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, UK.
Stefan HubscherDepartment of Pathology, University of Birmingham, Birmingham, UK.
Mark CallawayDivision of Diagnostics and Therapies, University Hospitals Bristol NHS Trust, Bristol, UK.
Dinesh SharmaRoyal Free Hospital, London, UK.
Teik Choon SeeDepartment of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Maria HawkinsDepartment of Medical Physics and Biomedical Engineering, University College London, London, UK.
Suzanne Ford-DunnWestern Sussex Hospitals NHS Foundation Trust, Worthing, UK.
Sarah SelemaniKing's College Hospital NHS Foundation Trust, London, UK.
Tim MeyerDepartment of Oncology, University College, London, UK.ORCID 0000-0003-0782-8647

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Deaths from the majority of cancers are falling globally, but the incidence and mortality from hepatocellular carcinoma (HCC) is increasing in the United Kingdom and in other Western countries. HCC is a highly fatal cancer, often diagnosed late, with an incidence to mortality ratio that approaches 1. Despite there being a number of treatment options, including those associated with good medium to long-term survival, 5-year survival from HCC in the UK remains below 20%. Sex, ethnicity and deprivation are important demographics for the incidence of, and/or survival from, HCC. These clinical practice guidelines will provide evidence-based advice for the assessment and management of patients with HCC. The clinical and scientific data underpinning the recommendations we make are summarised in detail. Much of the content will have broad relevance, but the treatment algorithms are based on therapies that are available in the UK and have regulatory approval for use in the National Health Service.

Indexed as

Carcinoma, HepatocellularLiver NeoplasmsAdultChemoembolization, TherapeuticGastroenterologyHumansLiver TransplantationUnited KingdomCANCERCANCER SUSCEPTIBILITYCHRONIC LIVER DISEASEMOLECULAR ONCOLOGYSURGICAL ONCOLOGY

Identifiers

PMID38627031
PMCPMC11287576

What Socratic holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.