Evidence map›Paper›PMID 38627839›Full record

ArticleJournal of cardiothoracic surgery2024

Diagnostic value of the creatine kinase-MB/creatine kinase and neutrophil/lymphocyte ratios in acute myocardial infarction.

Yin Liu, Xiao-Lei Tang, Yong Ni, Li-Zhong Duan, Feng-Jun Jing

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiothoracic surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Cardiac Modulation byCurrent issues in molecular biology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Yin LiuClinical laboratory, Traditional Chinese Medicine Hospital of Wuhu, Wuhu, 241000, China.
Xiao-Lei TangScience and technology department, The Second Affiliated Hospital of Wannan Medical College, No.10, Kangfu Road, Jinghu district, Wuhu City, 241000, Anhui Province, China. tangxiaolei_2023@163.com.
Yong NiClinical laboratory, Traditional Chinese Medicine Hospital of Wuhu, Wuhu, 241000, China.
Li-Zhong DuanClinical laboratory, Traditional Chinese Medicine Hospital of Wuhu, Wuhu, 241000, China.
Feng-Jun JingClinical laboratory, Traditional Chinese Medicine Hospital of Wuhu, Wuhu, 241000, China.
Honghu Hospital of Traditional Chinese Medicine · CNWannan Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the clinical significance of the creatine kinase (CK)-MB/total CK ratio, neutrophil/lymphocyte ratio (NLR) and red blood cell distribution width in acute myocardial infarction (AMI).

methodsA retrospective analysis was conducted of 196 AMI cases from our hospital's cardiology department; healthy people were selected over the same period as the control. The two groups' test indexes were compared through multivariate logistic regression analysis to screen for AMI risk factors; the receiver operating characteristic (ROC) curve was used to evaluate their AMI predictive values.

resultsThe serum CK, CK-MB, CK index, neutrophils and NLR values in the AMI group were significantly higher compared with those in the control group (p < 0.05); however, the levels of serum lymphocytes were significantly lower compared with those in the control group (p < 0.05). Multivariate logistic regression analysis showed that elevated CK-MB and NLR levels were risk factors for AMI (p < 0.05). The ROC curve showed that the area under the curve of the NLR and CK levels were 0.917 and 0.594, respectively.

conclusionThe CK index and NLR have a clinical predicting value for AMI and could be used as a clinical auxiliary diagnostic index for the assessment of patients with AMI.

Indexed as

Myocardial InfarctionNeutrophilsBiomarkersCreatine KinaseCreatine Kinase, MB FormHumansLymphocytesRetrospective StudiesROC CurveSensitivity and SpecificityBiomarkersCreatine KinaseCreatine Kinase, MB FormAcute myocardial infarctionCK-MB/CK rationeutrophil/lymphocyte ratio

Identifiers

PMID38627839
PMCPMC11020768
OpenAlexW4394847611

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.