Evidence mapPaperPMID 38630213Full record

GuidelineJournal of endocrinological investigation2024

Italian guidelines for the management of adult individuals with overweight and obesity and metabolic comorbidities that are resistant to behavioral treatment.

M Chianelli, L Busetto, R Vettor, B Annibale, A Paoletta, E Papini, A Albanese, M Carabotti, D Casarotto, G De Pergola and 25 more

Open access · hybridAbstract readPractice Guideline
PubMed Publisher
In one paragraph

Guideline in Journal of endocrinological investigation, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Dietitians' Perceptions of the Obesity Care Pathway: Qualitative Insights on Access, Follow-Up, and Referral of Patients Living With Obesity.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
    Article
  3. Article
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  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

35 authors at 18 institutions in 2 countries.

M Chianelli *Endocrinology, Regina Apostolorum Hospital, Albano Laziale, RM, Italy.ORCID http://orcid.org/0000-0002-8182-7071
L Busetto *Department of Medicine, Center for Medical and Surgical Therapy of Obesity, University of Padua, Padua University Hospital, President of the Italian Society for Obesity, Padua, Italy.ORCID http://orcid.org/0000-0003-4883-8980
R Vettor *Department of Medicine, Medical Clinic 3rd, Endocrine-Metabolic Unit, Padua University Hospital, Center for the Study and Integrated Treatment of Obesity, University of Padua, Padua, Italy.ORCID http://orcid.org/0000-0003-0625-6667
B AnnibalePresident of the Italian Society of Gastroenterology and Digestive Endoscopy, Department of Medico-Surgical Sciences and Translational Medicine, Unit of Diseases of the Digestive System and Liver, Sapienza University of Rome, Sant'Andrea University Hospital, Rome, Italy.ORCID http://orcid.org/0000-0001-9120-5957
A PaolettaEndocrinology, ULSS6 Euganea, Padua, Italy.
E PapiniEndocrinology, Regina Apostolorum Hospital, Albano Laziale, RM, Italy.ORCID http://orcid.org/0000-0003-4790-2733
A AlbaneseBariatric Surgery Unit, University Hospital of Padua, Padua, Italy.ORCID http://orcid.org/0009-0004-5712-3092
M CarabottiDepartment of Medical and Surgical Sciences and Translational Medicine, Sapienza University of Rome, Sant'Andrea University Hospital, Rome, Italy.ORCID http://orcid.org/0000-0001-9984-4630
D CasarottoUniversity Hospital of Padua, Padua, Italy.
G De PergolaClinical Nutrition Center for Research and Treatment of Obesity and Metabolic Diseases, IRCCS De Bellis, Castellana Grotte, BA, Italy.ORCID http://orcid.org/0000-0003-0020-3273
O E DisoteoDiabetology Unit, ASST Grande Ospedale Metropolitano Di Niguarda, Milan, Italy.ORCID http://orcid.org/0000-0002-9369-2629
I GrandoneDiabetology, Dietology and Clinical Nutrition Unit, Santa Maria Hospital, Terni, Italy.
G MedeaGeneral Practitioner, ATS Brescia, Brescia, Italy.ORCID http://orcid.org/0009-0004-2034-6495
E NisoliCenter for the Study and Research on Obesity, Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy.ORCID http://orcid.org/0000-0002-6670-1630
M RaffaelliEndocrine and Metabolic Surgery Unit, Agostino Gemelli IRCCS University Polyclinic Foundation, Center for Research in Endocrine Gland and Obesity Surgery, Catholic University of the Sacred Heart, Rome, Italy.ORCID http://orcid.org/0000-0002-1259-2491
S SchiffDepartment of Medicine-DIMED, University of Padua, Padua, Italy.ORCID http://orcid.org/0000-0003-1851-4299
F VignatiEndocrine Diseases and Diabetology Unit, Referral Center for the Study, Diagnosis and Treatment of Obesity, Sant'Anna Hospital, ASST Lariana, Como, Italy.
M CinquiniIstituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.ORCID http://orcid.org/0000-0003-4452-9478
M Gonzalez-LorenzoIstituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.ORCID http://orcid.org/0000-0002-0872-3858
V A FittipaldoIstituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.ORCID http://orcid.org/0000-0002-2832-9241
S MinozziIstituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.ORCID http://orcid.org/0000-0003-0471-8581
M MonteforteIstituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.ORCID http://orcid.org/0000-0002-1591-7810
A C TralongoIstituto di Ricerche Farmacologiche Mario Negri IRCCS, Milan, Italy.ORCID http://orcid.org/0000-0002-9577-1806
R NovizioEndocrinology and Metabolism Unit, Catholic University of the Sacred Heart, Rome, Italy. robertonovizio@gmail.com.ORCID http://orcid.org/0000-0001-5641-6847
A PersichettiMinistry of Interior - Department of Firefighters, Public Rescue and Civil Defense, Rome, Italy.ORCID http://orcid.org/0000-0003-2856-3764
I SamperiEndocrinology, ASL Novara, Novara, Italy.
A ScoppolaUOSD Endocrinologia ASL, Roma 1, Rome, Italy.ORCID http://orcid.org/0000-0002-6490-0978
G BorrettaDepartment of Endocrinology, Diabetes and Metabolism, Santa Croce and Carle Hospital, Cuneo, Italy.
M CarrubaCenter for the Study and Research on Obesity, Department of Medical Biotechnology and Translational Medicine, University of Milan, Milan, Italy.ORCID http://orcid.org/0000-0003-4589-387X
M G CarbonelliDietetics and Nutrition Unit, San Camillo-Forlanini Hospital, Rome, Italy.
M De LucaDepartment of General Surgery, Rovigo Hospital, Rovigo, Italy.ORCID http://orcid.org/0000-0001-7642-0915
S FrontoniEndocrinology Diabetes and Metabolism Unit, Fatebenefratelli Hospital, Rome, Italy.
S G CorradiniGastroenterology, Department of Translational and Precision Medicine, "Sapienza" University of Rome, Policlinico Umberto I University Hospital, Rome, Italy.ORCID http://orcid.org/0000-0002-0839-1961
F MuratoriEndocrine Diseases and Diabetology Unit, Referral Center for the Study, Diagnosis and Treatment of Obesity, Sant'Anna Hospital, ASST Lariana, Como, Italy.ORCID http://orcid.org/0000-0002-5153-8033
R AttanasioAME Scientific Committee, Milan, Italy.ORCID http://orcid.org/0000-0002-1417-287X
Mario Negri Institute for Pharmacological Research · ITUniversity of Padua · ITAzienda Socio Sanitaria Territoriale Lariana · ITOspedale Regina Apostolorum · ITSapienza University of Rome · ITUniversity of Milan · ITASL Roma · ITAzienda Sanitaria Ospedaliera S.Croce e Carle Cuneo · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITCarlo Forlanini Hospital · ITFatebenefratelli Hospital · ITGastroenterology Hospital "Saverio de Bellis" · ITMinistry of Interior · ITNovamont (Italy) · ITPoliclinico Umberto I · ITSanta Maria Nuova Hospital · ITUniversità Cattolica del Sacro Cuore · ITUniversity of the Sacred Heart · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThis guideline (GL) is aimed at providing a clinical practice reference for the management of adult patients with overweight or obesity associated with metabolic complications who are resistant to lifestyle modification.

methodsSurgeons, endocrinologists, gastroenterologists, psychologists, pharmacologists, a general practitioner, a nutritionist, a nurse and a patients' representative acted as multi-disciplinary panel. This GL has been developed following the Grading of Recommendations Assessment, Development and Evaluation (GRADE) approach. A systematic review and network meta-analysis was performed by a methodologic group. For each question, the panel identified potentially relevant outcomes, which were then rated for their impact on therapeutic choices. Only outcomes classified as "critical" and "important" were considered in the systematic review of evidence. Those classified as "critical" were considered for clinical practice recommendations. Consensus on the direction (for or against) and strength (strong or conditional) of recommendations was reached through a majority vote.

resultsThe present GL provides recommendations about the role of both pharmacological and surgical treatment for the clinical management of the adult patient population with BMI > 27 kg/m

conclusionThe present GL is directed to all physicians addressing people with obesity-working in hospitals, territorial services or private practice-and to general practitioners and patients. The recommendations should also consider the patient's preferences and the available resources and expertise.

Indexed as

ObesityOverweightAdultBariatric SurgeryBehavior TherapyComorbidityDisease ManagementHumansItalyNetwork Meta-Analysis as TopicSystematic Reviews as TopicBariatric surgeryLiraglutideNaltrexone–bupropionObesityOrlistatSemaglutide

Identifiers

PMID38630213
OpenAlexW4394873183

What Socratic holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.