Evidence map›Paper›PMID 38632902›Full record

ArticleJournal of natural products2024

Psammaplin A and Its Analogs Attenuate Oxidative Stress in Neuronal Cells through Peroxisome Proliferator-Activated Receptor γ Activation.

Rebeca Alvariño, Amparo Alfonso, Jioji N Tabudravu, Jesús González-Jartín, Khalid S Al Maqbali, Marwa Elhariry, Mercedes R Vieytes, Luis M Botana

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of natural products, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.5field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 citations in OpenAlex.

  1. EFE-8c4, a polyamine fromFrontiers in neuroscience · 2026
    Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Rebeca AlvariñoDepartamento de Fisiología, Facultad de Veterinaria, IDIS, Universidad de Santiago de Compostela, Lugo 27002, España.ORCID 0000-0001-8796-1389
Amparo AlfonsoDepartamento de Farmacología, Facultad de Veterinaria, IDIS, Universidad de Santiago de Compostela, Lugo 27002, España.ORCID 0000-0003-1572-9016
Jioji N TabudravuSchool of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, Lancashire PR1 2HE, United Kingdom.ORCID 0000-0002-6930-6572
Jesús González-JartínDepartamento de Farmacología, Facultad de Veterinaria, IDIS, Universidad de Santiago de Compostela, Lugo 27002, España.ORCID 0000-0003-2882-504X
Khalid S Al MaqbaliSchool of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, Lancashire PR1 2HE, United Kingdom.
Marwa ElharirySchool of Pharmacy and Biomedical Sciences, University of Central Lancashire, Preston, Lancashire PR1 2HE, United Kingdom.
Mercedes R VieytesDepartamento de Fisiología, Facultad de Veterinaria, IDIS, Universidad de Santiago de Compostela, Lugo 27002, España.
Luis M BotanaDepartamento de Farmacología, Facultad de Veterinaria, IDIS, Universidad de Santiago de Compostela, Lugo 27002, España.
Universidade de Santiago de Compostela · ESUniversity of Lancashire · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psammaplins are sulfur containing bromotyrosine alkaloids that have shown antitumor activity through the inhibition of class I histone deacetylases (HDACs). The cytotoxic properties of psammaplin A (

Indexed as

DisulfidesOxidative StressPPAR gammaAlkaloidsAnimalsAntioxidantsCatalaseGlutathioneGlutathione PeroxidaseHistone Deacetylase 3Histone DeacetylasesHumansMembrane Potential, MitochondrialMitochondrial Membrane Transport ProteinsMolecular StructureNeuronsAlkaloidsAntioxidantsCatalaseDisulfidesGlutathioneGlutathione PeroxidaseHistone Deacetylase 3Histone DeacetylasesMitochondrial Membrane Transport ProteinsNF-E2-Related Factor 2PPAR gammapsammaplin AReactive Oxygen SpeciesTyrosine

Identifiers

PMID38632902
PMCPMC11061836
OpenAlexW4394921443

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.