Evidence map›Paper›PMID 38635628›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2024

Parkinsonism Sac domain mutation in Synaptojanin-1 affects ciliary properties in iPSC-derived dopaminergic neurons.

Nisha Mohd Rafiq, Kenshiro Fujise, Martin Shaun Rosenfeld, Peng Xu, Pietro De Camilli

Open access · hybridAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
2.9field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Roles in physiology and disease of the inositol phosphatase synaptojanin 1.Biochimica et biophysica acta. Molecular and cell biology of lipids · 2026
    Review
  7. Article
  8. Regulation of yeast polarized exocytosis by phosphoinositide lipids.Cellular and molecular life sciences : CMLS · 2024
    Review
  9. Parkinsonism Sac domain mutation in Synaptojanin-1 affects ciliary properties in iPSC-derived dopaminergic neurons.Proceedings of the National Academy of Sciences of the United States of America · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nisha Mohd RafiqDepartment of Neuroscience, Yale University School of Medicine, New Haven, CT 06510.ORCID 0000-0002-4434-0504
Kenshiro FujiseDepartment of Neuroscience, Yale University School of Medicine, New Haven, CT 06510.ORCID 0000-0001-9018-6504
Martin Shaun RosenfeldDepartment of Neuroscience, Yale University School of Medicine, New Haven, CT 06510.
Peng XuDepartment of Neuroscience, Yale University School of Medicine, New Haven, CT 06510.ORCID 0000-0001-5197-9560
Pietro De CamilliDepartment of Neuroscience, Yale University School of Medicine, New Haven, CT 06510.ORCID 0000-0001-9045-0723
Yale University · US

Funding

Yale/NIDA Neuroproteomics Research CenterP30DA018343 · NIDA · YALE UNIVERSITY · PI ANGUS C. NAIRN, Kenneth Robert WILLIAMS · 2004 to 2026
$37.1M
MOLECULAR MECHANISMS IN SYNAPTIC VESICLE RECYCLINGR01NS036251 · NINDS · YALE UNIVERSITY · PI DE CAMILLI, PIETRO · 1997 to 2021
$4.7M
Molecular Mechanisms in Synaptic Vesicle RecyclingR37NS036251 · NINDS · YALE UNIVERSITY · PI DE CAMILLI, PIETRO · 2010 to 2016
$2.7M
NIDA NIH HHS P30 DA018343NINDS NIH HHS R01 NS036251NINDS NIH HHS R37 NS036251
6 · The paper itself

Abstract

Synaptojanin-1 (SJ1) is a major neuronal-enriched PI(4, 5)P

Indexed as

Induced Pluripotent Stem CellsNerve Tissue ProteinsParkinson DiseaseParkinsonian DisordersAnimalsDopaminergic NeuronsHumansMiceMutationPhosphoric Monoester HydrolasesNerve Tissue ProteinsPhosphoric Monoester Hydrolasessynaptojanincalcium channelcentrioleParkinson’s diseasephosphoinositidesprimary cilia

Identifiers

PMID38635628
PMCPMC11047088
OpenAlexW4394909958

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.