Evidence map›Paper›PMID 38638910›Full record

ArticleFrontiers in microbiology2024

Regulation of Wnt/β-catenin signaling by Marek's disease virus

Haiyin Xu, Xihao Xu, Huifeng He, Hongxia Shao, Yongxiu Yao, Aijian Qin, Kun Qian

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Haiyin XuMinistry of Education Key Laboratory for Avian Preventive Medicine, Yangzhou University, Yangzhou, China.
Xihao XuMinistry of Education Key Laboratory for Avian Preventive Medicine, Yangzhou University, Yangzhou, China.
Huifeng HeMinistry of Education Key Laboratory for Avian Preventive Medicine, Yangzhou University, Yangzhou, China.
Hongxia ShaoMinistry of Education Key Laboratory for Avian Preventive Medicine, Yangzhou University, Yangzhou, China.
Yongxiu YaoThe Pirbright Institute & UK-China Centre of Excellence for Research on Avian Diseases, Surrey, United Kingdom.
Aijian QinMinistry of Education Key Laboratory for Avian Preventive Medicine, Yangzhou University, Yangzhou, China.
Kun QianMinistry of Education Key Laboratory for Avian Preventive Medicine, Yangzhou University, Yangzhou, China.
Yangzhou University · CNThe Pirbright Institute · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Marek's disease virus (MDV) infection causes immunosuppression in the host, ultimately inducing tumor formation and causing significant economic losses to the poultry industry. While the abnormal activation of the Wnt/β-catenin signaling pathway is closely associated with the occurrence and development of tumors. However, the relationship between MDV and the Wnt/β-catenin pathway remains unclear. In this study, we found that the MDV RB1B strain, but not the MDV vaccine strain CVI988, activated the Wnt/β-catenin signaling pathway by increasing the phosphorylation level of GSK-3β in chicken embryo fibroblast (CEF).

Indexed as

CVI988Marek’s disease virusMeqRB1BWnt/β-catenin signaling pathway

Identifiers

PMID38638910
PMCPMC11025357
OpenAlexW4393866855

What Socratic holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the Socratic graph.